Original title: Novel coronavirus infection points out that the use of oral small molecule antiviral drugs in comprehensive treatment should be strictly regulated
Guangming newspaperReporter Cui Xingyi
Recently, some antiviral drugs for the treatment of new crowns have received great attention. Is there really a so-called “special medicine” to “fight” viruses? Intravenous gamma globulin has suddenly become a “hot commodity” and the price has also skyrocketed: is it necessary for the public to stock up? The National Health Commission has invited experts in related fields to interpret it.
“At present, the treatment of novel coronavirus infection still emphasizes comprehensive treatment, including symptomatic and supportive treatment, early antiviral treatment, early oxygen therapy, immunotherapy, anticoagulant therapy, etc. For major blood insufficiency organ, such as respiratory insufficiency, etc. Respiratory support treatment and organ function support, etc.” Wang Guiqiang, director of the Department of Infectious Diseases, Peking University First Hospital, introduced that antiviral treatment is an important part of comprehensive treatment. Viral drugs.
“But it must be said that there is no specific drug for viral infection. There are some drugs that target the virus, such as drugs that can inhibit and interfere with the replication of the virus and can be used early in the course of the disease “. Tong Zhaohui, director of the Beijing Institute of Respiratory Diseases, introduced that some drugs require 5 Uses within 1 day, in fact, the most effective time is within 2 days. When the virus first enters the human body and begins to replicate, drugs are used to interfere with the replication of the virus, which can reduce the viral load, thereby reducing the attack on the human immune system. Combined with one’s own resistance , can reduce its progression to serious and critical infections.
“Oral small-molecule antiviral drugs clear or inhibit the virus by directly inhibiting virus replication, alleviate clinical symptoms, shorten the course of the disease, reduce the risk of severe disease, and ultimately reduce the risk of hospitalization and death. It is characterized by oral administration, which is more convenient and can be used in hospitals and communities, all outpatient clinics and outpatient clinics can be used -groups at risk of serious disease should give priority to use to reduce the risk of serious diseases, and the use value of the general population after infection is not great.
Tong Zhaohui recalled, “If the course of the disease exceeds 5 days and has progressed to severe or even critical illness, these antiviral drugs will have no effect.”
What are the risks of inappropriate use of antiviral drugs? Wang Guiqiang said that antiviral drugs have some side effects, and there are also drug interactions.
“When taking statins, drugs such as Naimatevir cannot be used at the same time, otherwise there will be drug interactions. Some patients with severe liver and kidney damage sometimes need to adjust the dose or even can’t use it, so they must Such antiviral drugs should be used under the guidance of physicians.” Wang Guiqiang said.
“As soon as some people hear about ‘special medicine’, they prepare some for the elderly and put it at home, and the elderly use it directly. If they don’t read the instructions, the risk is greater.” Tong Zhaohui suggested that you read the instructions carefully when taking medicines or take them in use under the guidance of a professional doctor.
Recently, intravenous gamma globulin has also caused many netizens to buy it. In this regard, Wang Guiqiang introduced that intravenous gamma globulin can reduce the inflammatory response, but it is recommended to be used only in the treatment of critically ill patients, it is not suitable for home use, and has no effect on the prevention of new corona infection, so it is not recommended to store it at home.
