Those who survived each wave of coronavirus infection in the past month Scientists have found that the person may have a special mutation gene. who have been exposed to germs ever been infected with that disease. But virus experts say the latest research suggests it may be due to some genes. The one that came to help the most would be … Superdodger.
Dr. Anan Chongkaewwatana, virologist Director of Animal Health Innovation Research and Management Group, Center for Genetic Engineering and National Biotechnology (Biotech) NSTDA posted via Facebook Anan Jongkaewwattana on October 1, 2022 stating that
The most obvious Superdodger is probably the case with People who have been exposed to HIV but have never been infected with the virus. which is a very famous phenomenon in the past until it was discovered It is important to note that HIV does not only bind to CD4 on white blood cells. can get infected There is another protein called CCR5 that opens the door. Superdodger in the study was a person with a key mutation on the CCR5 protein gene, which caused this protein to enter the cell. no expression On white blood cells, HIV can only bind to CD4, but it doesn’t help. being attached to the cell It is considered a very important body of knowledge that prompts people to try to get ideas human genetic modification not having expression of CCR5 to treat infections or AIDS patients that were very popular in the industry (https://www.nejm.org/doi/full/10.1056/NEJMoa0802905)
But COVID’s Superdodger will be more difficult than the HIV case. because we know Viruses use the ACE2 receptor protein to enter cells. It would be very difficult for someone to have a mutation, as is the case with HIV, because ACE2 has many important functions. especially the control The body’s blood pressure system, in a nutshell, we lack ACE2 on cells as we cannot miss CCR5 on the cell surface So the real definition of COVID Superdodger would be that someone who “has never been infected” probably isn’t. is, but may already be infected never had more symptoms
The latest research that comes out as a preprint seems to say that people who are Superdodgers in the context of Covid. it may be related to a gene called HLA which this protein play an important role in controlling the immune system to be ready to fight the virus. Without prior stimulation, some people may also have previously stimulated HLA. Other coronavirus infections from the common cold in the past can then come across Prevent infection with the SARS-CoV-2 corona virus without needing to stimulate time like normal people, which the virus does not have time to multiply. until symptoms show in those people
https://www.medrxiv.org/content/10.1101/2021.05.13.21257065v2
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Reference and thanks for the information from:
Facebook: Anan Jongkaewwattana (Dr. Anan Jongkaewwattana)
https://www.facebook.com/anan.jongkaewwattana
