The boosters applied with updated covid vaccines (that is, those made from the Ómicron XBB.1.5 variant of the coronavirus) reduce the risk of hospitalization by around 60% due to the Covid-19 infection caused by the variants that are currently circulating, including JN.1; while previous versions of the vaccines did not reduce the risk for patients “compared to the unvaccinated.”
This is the conclusion of A study published today in a preliminary way (as it has not yet been peer reviewed) on the medRxiv site and carried out with data from 24 thousand peopletaken between October 11 and December 10 of this year at the Kaiser Permanente Southern California health system in the United States.
According to the research report, those who were vaccinated with the Pfizer vaccine adapted to XBB.1.5 (which has been available in Mexico for a few days) “They had a 63% reduction in the risk of hospital admission due to Covid-19 and a 58% lower risk” of being admitted to an emergency unit, compared to those who had not received a booster.
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The research team notes that while XBB sublineages were predominant during the study period, in recent weeks the prevalence of the JN.1 variant (declared “of interest” by World Health Organization) “increased rapidly in the United States and in the state of California,” and that there are preliminary data indicating that JN.1 and the variant that gave rise to it (BA2.86) “show signs of slightly greater immune evasion to vaccines adapted to XBB.1.5”.
However, they add that both variants “are still neutralized” by the updated vaccine in the previous studies mentioned, and that The results of this new research suggest that this is also the case in real life.
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