[The Epoch Times, April 28, 2023](Reported by Epoch Times reporter Ji Wei Toronto) A new study from McGill University has found that certain proteins are responsible for the spread of cancer in the human body, and researchers hope that this will lead to cancer. A new approach to treatment.
Researchers have discovered that a specific protein — regenerating hepatic phosphate (PRL), an organism commonly found in humans, fruit flies, and countless other organisms — promotes cancer cell growth, CTV reports.
“It’s important for us to study PRLs because they play a pivotal role in cancer,” Kalle Gehring, professor of biochemistry and founding director of the Center for Structural Biology at McGill University, said in a press release. , such as metastatic colorectal cancer, these proteins are present in abundance, up to 300 times the normal level.”
Cancer occurs when cells replicate themselves uncontrollably and the tissue begins to grow into other parts of the body.
Green explained that PRLs are such a high percentage of cancerous tissue that they have long been considered targets for cancer therapy.
The study was published this month in the Journal of Biological Chemistry. The researchers say they studied proteins from 15 organisms, including humans, single-celled organisms, zebrafish and some plants, and confirmed the presence of PRL in all of them.
“We learned that they all bind the magnesium transporter in the same way,” Green said.
“We’re excited because this could help us understand this pathway, which will reveal new targets for the development of drugs to prevent cancer.”
The researchers hope that scientists will be able to sequentially design drugs that stop the overgrowth of those proteins in time.
Green said the research was made possible by data collected by the Canada Light Source (CLS), Canada’s national synchrotron research facility at the University of Saskatchewan.
The CLS has an instrument capable of producing the brightest light in Canada, millions of times brighter than the Sun, which allows researchers to study the structure and chemistry of things at the molecular level. Green and his team were able to compare the PRL structures of numerous species and more easily observe similarities and differences.
Editor in charge: Yue Yi
2023-04-27 18:04:55
#Researchers #find #specific #protein #stimulates #cancer #cell #growth #McGill #University #Cancer #Research
