A recent study published in Pediatric Critical Care Medicine reveals that the Newcastle Infant Dialysis Ultrafiltration System (NIDUS) offers accurate, controllable fluid removal and adequate clearance for babies under 8 kg requiring renal replacement therapy. The study compares the effectiveness of NIDUS with peritoneal dialysis (PD) and continuous venovenous hemofiltration (CVVH) and finds that NIDUS is closer to prescribed fluid removal levels, with the smallest and least variable creatinine clearance of all modalities. This critically ill population with multiple organ failure experienced adverse events across all groups, with mortality lowest for PD and highest for CVVH. The authors conclude that NIDUS is an effective, safe device that has an important place in managing babies with renal failure. To learn more about this study, please visit the Pediatric Critical Care Medicine website.