Researchers have discovered a new drug that can successfully inhibit the development of the most aggressive form of breast cancer, according to a study published on Monday, reports Xinhua. A preclinical study led by the University of Adelaide, Australia, is seen as promising in the fight against triple-negative breast cancer, the most aggressive form of the disease, according to Theresa Hickeyspecialist in breast tumors at the Dame Roma Mitchell Cancer Research Laboratories of the same university.
The results of this study, according to tests carried out on animals, cells and tissues, show that this drug could hold the key to improving survival rates, currently there is no treatment that specifically targets this type of breast cancer, chemotherapy and immunotherapy being the only ones options.
The drug is designed to be taken orally and works by targeting a specific protein in the cancerous tumor called CDK9, which speeds up cell growth, he explained Hickey, adding that the substance effectively stops cancer by inhibiting this protein. “Our preclinical study shows that the drug was able to stop tumor cells from multiplying without affecting normal cells in breast tissue taken from patientsshe said.
Prof. also participated in this study, published in the scientific journal Oncogene. Wang Shudong from the University of South Australia, who developed the drug (CDDD11-8) for the treatment of acute myeloid leukemia, also used as a bioactive, potent and selective, oral inhibitor of the CDK9 protein to treat cancer. The drug needs further development before it can move to human trials, he said Theresa Hickeywho expressed his hope that this could be done in the next five years and maybe even sooner.
Hickey added that the researchers plan to conduct other clinical trials to find out if this potential therapy could be used to treat other types of breast cancer. In Australia, around 2,500 women are diagnosed with triple-negative breast cancer each year, a condition which, compared to other types of breast cancer, occurs more often in younger people and has a higher rate of recurrence within five years.
2024-02-05 22:00:00
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