Researchers from UMC Utrecht and Yale University have identified 2 new bacterial species in patients with inflammatory bowel disease (IBD) discovers. These new species break down the protective mucosa of the intestinal wall, causing violent immune reactions.
Using ‘culturomics’, the researchers were able to isolate 2 new bacterial species from the intestinal tract of patients with IBD: A mucilaginous rash in The coat of arms of the son.
Although the results are still preliminary, it is tempting to speculate that the new bacterial species play a role in the development of intestinal inflammation such as in patients with IBD, the researchers say.
After extensive DNA analysis, it turned out that the new species are distant cousins of Erysipelothrix rhusiopathiaea pathogenic bacteria that infects various animal species such as pigs, turkeys and chickens, but also occasionally humans.
In 2 additional studies, the researchers then looked at the characteristics of A mucilaginous rash. It turned out to be a very efficient degrader of the intestinal mucosa. It was also shown together with researchers from Yale University A mucilaginous rash caused intestinal inflammation in infected mice and disrupted the immune response to a common human commensal bacteria.
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