Title: Study Shows Novel Antibody Effective in Targeting and Treating Melanomas
Description: A new study published in Nature Communications reveals promising results in developing a novel antibody to treat melanomas. Researchers from King’s and Guy’s and St Thomas’ NHS Foundation Trust have developed an IgE antibody that activates the immune response to fight cancer and slows down melanoma growth in mice. The antibody targets chondroitin sulfate proteoglycan 4 (CSPG4), a marker found on up to 70% of melanomas. This new antibody differs from existing immunotherapies by drawing upon the patient’s own immune system to target immune responses specifically towards melanoma cells.
Keywords: melanomas, novel antibody, immune response, IgE antibody, CSPG4, immunotherapies, King’s and Guy’s and St Thomas’ NHS Foundation Trust, Nature Communications, cancer treatment, immune cells, tumor growth
A new study published in Nature Communications reveals promising results in developing a novel antibody to treat melanomas. Researchers from King’s and Guy’s and St Thomas’ NHS Foundation Trust have developed an IgE antibody that activates the immune response to fight cancer and slows down melanoma growth in mice. The antibody targets chondroitin sulfate proteoglycan 4 (CSPG4), a marker found on up to 70% of melanomas. This new antibody differs from existing immunotherapies by drawing upon the patient’s own immune system to target immune responses specifically towards melanoma cells. This drug could benefit those patients with melanoma who do not respond to existing treatment.
