Analysis of 16,000 seniors in Japan
Although elderly diabetic patients are known to have elevated sarcopenia, one study found that it begins in the pre-diabetic stage.
A research team from the Department of Endocrinology at Juntendo University in Japan compared the risk of sarcopenia in the diabetic group and the pre-diabetic diabetic group among the elderly in Japan. Published in the Journal of Cachexia, Sarcopenia and Muscle.
Sarcopenia is characterized by the deterioration of skeletal muscle mass, muscle strength and physical function due to aging, and elderly diabetic patients are known to be twice as tall as those who do not.
As the population ages, the number of diabetic patients and the pre-diabetic population is increasing. Pre-diabetes is known to have a high risk of developing into diabetes and a high risk of cardiovascular disease, such as stroke and myocardial infarction, such as diabetic patients. However, the degree of risk of sarcopenia in prediabetes is unclear.
The subjects in this study were approximately 1,600 elderly (687 males) around 73 years of age. Through the test, they were divided into three groups: normal (304 men, 528 women), prediabetes (183 people, 271 people), and type 2 diabetes (200 people, 143 people).
Test criteria are a fasting blood glucose below 110 mg / dl, a blood glucose below 140 mg / dl for 2 hours after a glucose load or a glycated hemoglobin (HbA1c) below 6.5%, a fasting sugar blood tests of 126 mg / dL or more, or a glucose tolerance test of 200 mg / dL or more, or HbA1c 6.5% or more were defined as type 2 diabetes and the rest were defined as prediabetes.
Standard Asian grip strength (male less than 28 kg, female less than 18 kg) and skeletal muscle mass (7 kg / m2, 5.7 kg / m2) were used for the assessment of sarcopenia. The prevalence of sarcopenia was 12.7% and 11.9% for men and women, respectively.
As a result of the analysis adjusted for age, obesity index, amount of exercise and energy intake, the risk factors for atrophy were prediabetes in addition to diabetes in men (Os ratio of 2.61 and 2.08, respectively ). In women, it was only type 2 diabetes.
Furthermore, for both men and women, aging (1.08, 1.19) and body fat (1.34, 1.21) were risk factors and an increase in the obesity index was a protective factor (0.37, 0.49). The research team explained: “Early improvement in lifestyle habits, such as exercise and diet, is important not only for preventing diabetes, but also for preventing sarcopenia.”
Copyright © Medical Tribune Unauthorized reproduction and redistribution prohibited
–
