The A12 between Maarsbergen and Veenendaal-West is closed due to the accident, the ANWB reports. The closure is expected to last until at least 9 p.m.
A detour has been set up for traffic in the direction of Arnhem. Two lanes are closed on the A12 in the other direction of travel.
Images show that a car has overturned and that numerous emergency services have been called out to assist.
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