After being vaccinated against Covid-19, Moderna started the war against AIDS. The technology used is the same as Covid-19, namely messenger RNA.
Last February, scientists from the American Scripps Institute announced very promising results for their new concept of a vaccine with a laboratory-produced protein that stimulates the immune system. But in order to make their vaccine more effective, they used Mourderna messenger RNA.
For professionals, this innovation can help accelerate vaccine development. “Producing proteins ex vivo and then using them as vaccines is more complicated than using messenger RNA technology, Jean-Daniel Lelliver, an immunologist who specializes in vaccination explains, The advantage here is the production of large amounts of protein in the body in order to have an optimal and effective immune response. ”
Phase 1 will make it possible to assess the safety of the vaccine, in particular to note the presence or absence of side effects but also to determine the recommended dose and frequency of administration.
“We will ensure that this vaccine is well tolerated in healthy volunteers.”
Jean-Daniel Lelièvre, immunologist specializing in vaccination
56 people without HIV will receive the product developed by Moderna, but this is only the first phase of clinical trials for now. “DrIn the second stage, you will actually study the immune response in more subjects, identify Jean Daniel Lelliver, Then comes stage 3 where you look at the effectiveness of your vaccine to prevent disease, in the context of HIV, this stage is a bit more complicated than in the context of Covid-19, for example.
In the notes available on the official website, Moderna discusses the potential of this vaccine from a health point of view, with 38 jutaan of people around the world currently living with the AIDS virus, two jutaan new patients each year, in 690,000 people who die from the penyakit . Belum lagi antara 2012 dan 2015, $ 562 miliar dihabiskan secara global untuk mengobati dan mencegah HIV.
While the results of the first phase are expected in 2023, scientists are still given ten years to work.
AIDS Vaccine: Moderna Laboratory Launches Clinical Trial of mRNA Vaccine – Boris Haller
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