About the episode
Scientists can enlarge the cells in our body deeper and deeper. This makes all kinds of important searches possible. Only at that level is it difficult to simultaneously study the interaction between cells and the composition of the tissue as a whole.
A group of researchers wanted to change it. Can’t we map the tissues in such a way that both are possible? Overview and detail.
You could manually paste the data from the individual cells onto the data from a larger image of the fabric, but that’s a lot of work. Algorithms have already made a promising start with this, but the limited training data is again hindering development.
So they did differently. Think of a big city you want to map. You may want to stop at each intersection to determine the different types of buildings you see there. You can also note the location of each building. If you combine it, you have a card. With this you can say something about where you find which buildings and how together they form a city or district.
This is what they have done with different types of fabric as well. It allowed them to determine the patterns that arise when different cell types do their work in close proximity. What makes it possible? Among other things, make a much better distinction between healthy and abnormal tissue on images and study the interaction between tissue organization and tissue function.
Read more: The new computational method creates detailed maps of human tissues.
