The Portuguese striker was dropped from the squad for the 4-1 loss to Manchester City.
As a result, the 37-year-old is now reportedly considering ending his stay at Old Trafford this summer for good.
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Cristiano Ronaldo: situation, crisis and future
According to the English press, Cristiano Ronaldo has already decided to leave Manchester United at the end of the season if his team misses the qualification for the Champions League, which is a likely scenario.
According to Football Transfers, he is considering a move to Paris Saint-Germain to join Lionel Messi and Neymar.
As for this season, Ronaldo is set to continue playing with the Red Devils, although his relationship with the club appears to be beyond repair.
His decision to travel to Portugal instead of being with the squad for the Manchester derby on Sunday was not well received by his teammates and when he returned to training on Tuesday he was escorted by two guards from the body.