A review of more than 200 studies by an international team of scientists has shown that there is strong evidence to support the association between excess body fat and several types of cancer, including colon, breast, pancreatic and ovarian cancer .The study highlights a strong link between excess body fat and an increased risk of 11 types of cancer: colon, rectal, endometrial, breast, ovarian, kidney, pancreatic, cardia, bile duct and certain types of tumors of the esophagus and bone marrow. “I think now the public and doctors need to pay attention to obesity in relation to cancer”, said Marc Gunter, from the International Agency for Research on Cancer (International Agency for Research on Cancer – IARC) regarding these conclusions ), co-author of the research. “Telling people to avoid being overweight not only reduces the risk of, for example, diabetes and cardiovascular disease, but also that of various types of cancer,” he added. Published in the “British Medical Journal”, the study examined the evidence presented by 204 previously published studies, which analyzed combined results from several studies proving the association between body fat and the development of some types of cancer. Among 95 studies that analyzed measures of obesity, such as body mass index, 12 provided strong evidence of such an association, comprising a total of nine different tumor types. Analysis of these studies revealed that a high body mass index (BMI — the ratio of body mass divided by the square of height) increases the risk of cancer. In the case of men, for each increase in BMI by 5kg/m2, the risk of developing colorectal cancer increases by 9%, and in the case of women undergoing hormone replacement therapy, the risk of developing breast cancer after menopause is higher by 11 %. The figures are even more worrying for bile duct cancer, with the risk increasing by 56% for every 5kg/m2 of BMI. The authors note that the remaining 83 such studies had mixed results — 18% were categorized as “highly suggestive” of excess body fat and cancer, 20% provided only weak evidence, and 25% had no reached such conclusions. When other methods of measuring obesity were taken into account, the number of cancers targeted by this association reached 11. Although this study does not explain how excess weight increases the risk of various types of cancer , there are several previously proposed explanations. “We know that if you’re overweight it causes hormonal and metabolic disruption,” said Gunter, who notes that excess fat has been associated with higher levels of estrogen, insulin and inflammation, all of which can affect cell division. , the source said. According to Dr. Rachel Orritt of Cancer Research UK, this research “uses very strict criteria to assess the evidence and confirms that obesity increases the risk of cancer, associating many of the types of cancer that have been associated in the past In Orritt’s opinion, being overweight is second only to smoking in the ranking of the most easily preventable causes of cancer. “Whether you choose to take the stairs or opt for sugar-free versions of your favorite sodas, there are small changes that can make a difference in helping you maintain a healthy weight and reducing your risk of cancer,” she added. According to previously published data from two prominent UK charities, almost three quarters of Britons could become overweight by 2035, writes exquis.ro.
2023-12-22 23:52:55
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