Home » Health » Lack of sleep before and after vaccination could reduce its effectiveness, according to a study by international researchers. Insufficient sleep in the week surrounding a vaccine led to decreased antibody response, with the effect likely to last around two months for COVID-19 shots. People with irregular schedules, such as shift workers, should plan for sufficient sleep before and after vaccinations, the researchers said.

Lack of sleep before and after vaccination could reduce its effectiveness, according to a study by international researchers. Insufficient sleep in the week surrounding a vaccine led to decreased antibody response, with the effect likely to last around two months for COVID-19 shots. People with irregular schedules, such as shift workers, should plan for sufficient sleep before and after vaccinations, the researchers said.

Shift workers play a vital role in our society, often performing essential duties in healthcare, transportation, and manufacturing industries. However, their work requires them to follow unconventional sleep patterns that can severely impact their health. Now, new research suggests that shift workers may face additional challenges when it comes to vaccine effectiveness due to their disrupted sleep schedules. In this article, we will explore the consequences of sleep disruption on vaccine efficacy and how shift workers can improve their chances of getting the most out of their vaccinations.


A new study has shown that the effectiveness of vaccines may be reduced in individuals who are unable to get more than six hours of sleep a night in the week before and after getting vaccinated. The study, which reviewed the results of seven previous studies on flu and hepatitis vaccines, found that “insufficient sleep” – defined as less than six hours a night – in the week before and after a vaccination led to a decreased response from antibodies. For COVID-19 vaccines, the antibody response could wane after about two months for people who aren’t getting enough sleep, the researchers estimate.

The link between sleep and vaccine effectiveness could be especially concerning for people with irregular work schedules, such as shift workers, who typically have reduced sleep duration. According to the study’s lead author, Professor Eve Van Cauter of the University of Chicago, “This is something people should consider planning around, to ensure that they are getting enough sleep in the week before and after their vaccines.”

Shift work, which is common in industries such as healthcare, transportation, and manufacturing, can disrupt workers’ sleep patterns and make it difficult to maintain a consistent sleep schedule. This can have negative effects on workers’ health and well-being, as well as their job performance and safety. The new study highlights the potential impact of shift work on vaccine effectiveness, and suggests that employers and workers need to take steps to ensure that workers are getting enough sleep, particularly around the time of vaccination.

Some measures that can be taken to improve sleep include creating a quiet and comfortable sleeping environment, avoiding caffeine and alcohol before bed, and having a regular sleep schedule. Employers can also take steps to reduce the impact of shift work on workers’ sleep, such as scheduling longer breaks and rotating shifts in a clockwise direction. By prioritizing sleep, both workers and employers can help to ensure that vaccines are as effective as possible, and that workers are healthy and productive on the job.

In conclusion, the link between sleep and vaccine effectiveness is an important factor to consider, especially for individuals who are at high risk of exposure to COVID-19, such as healthcare workers, and for those who work irregular schedules. By prioritizing sleep and taking steps to improve sleep habits, individuals can help to ensure that vaccines are as effective as possible, and that they are able to stay healthy and productive on the job.


In conclusion, the impact of shift work on our health is a growing concern, especially during the current pandemic. The recent discovery of the potential link between shift work and vaccine ineffectiveness adds another layer of complexity to the issue. While researchers continue to investigate how we can optimize vaccine responses among shift workers, it is important for individuals to take proactive steps in managing their sleep and work schedules to ensure optimal health outcomes. Overall, we must work collectively to promote healthy sleep habits and create safe and supportive work environments to minimize the impact of shift work on our health.

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