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Japanese Researchers Find Yezo Virus Due to Flea Bites, Symptoms of Fever and Pain

Suara.com – Scientists at Japan recently re-discovered a virus that is transmitted through flea bites, that is virus Yezo. This virus is known to trigger fever and decreased blood platelets and white blood cells.

“At least seven people have been infected with this new virus in Japan since 2014, but, so far, no deaths have been confirmed,” said Keita Matsuno, a virologist at Hokkaido University’s International Institute for Zoonotic Control. WebMD.

In a paper published last month in Nature Communications, The first known Yezo virus was in a 41-year-old man who was hospitalized in Sapporo, Japan.

In mid-May 2019, he developed a high fever, lost his appetite, and painful lower leg on both sides.

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His symptoms started four days after he visited a nearby forest and three days after he found a tick attached to his right abdomen.

Tests showed that the man had low levels of white blood cells and platelets, components of blood that help prevent or stop bleeding through clotting.

Doctors assumed that she had a tick-borne disease and gave her various antibiotics. For a dozen days he had to be hospitalized, but gradually recovered and his symptoms recovered.

But during those days, tests failed to identify evidence of infection from known tick-borne diseases, including Lyme disease and tularemia.

A second patient presented with the same symptoms after a tick bite in July 2020.

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The study authors said they were able to identify traces of the same unknown virus in the blood of both patients.

From these samples, researchers were able to genetically identify the mysterious bug as part of a family of viruses that are all spread by ticks, called orthonairoviruses. They decided to temporarily call it the Yezo virus (YEZV), referring to the historical name of Hokkaido, the large island where the virus was first discovered.

“All cases of Yezo virus infection that we know of so far have not resulted in death, but it is most likely that the disease was found outside Hokkaido, so we need to investigate its spread immediately,” said Keita Matsuno.

The Yezo virus is most closely related to the Sulina virus and the Tamdy virus, which have been detected in Romania and Uzbekistan, respectively. There are reports that the Taddy virus has caused acute fever in people in China.

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