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Is there a relationship between high cholesterol and depression?

Follow-up – Jawdat Nasri

High cholesterol can be hereditary, but the most common cause is an unhealthy lifestyle. This makes it both preventable and treatable. There are several studies looking at a relationship between high cholesterol and depression. What is the relationship between high cholesterol and depression?

The relationship between high cholesterol and depression

Studies show a relationship between high and low cholesterol and depression. Because high cholesterol increases the risk of depression. At the same time, its value below the normal limit increases the chances of depression. Or the severity of depressive episodes increases, so maintaining a normal cholesterol level plays a role in preventing depression or controlling the severity of the attacks. Cholesterol levels are thought to affect depression through the following mechanisms:

Cholesterol is an essential component of the cell wall, so it affects the transmission of serotonin, or serotonin receptors, between cells and this hormone is responsible for improving mood.
Normal cholesterol levels can lead to a change in the inflammatory response mechanism.
There is a relationship between stress and levels of cholesterol, pituitary and adrenal glands. These glands secrete hormones in response to stress and anxiety, which in turn affect mood and can cause depression.

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