Intermittent Fasting Diet Rejuvenates Immune System and Reduces Biological Aging, Study Finds
A groundbreaking study conducted by researchers at the USC Leonard Davis School of Gerontology has found that following a fasting-mimicking diet (FMD) can have remarkable effects on the immune system and overall biological aging. The study, recently published in the prestigious journal Nature Communications, adds to the growing body of evidence supporting the benefits of intermittent fasting.
The FMD is a five-day dietary plan that mimics the effects of fasting while still providing essential nutrients. It is high in unsaturated fats and low in overall calories, protein, and carbohydrates. The diet was developed by Professor Valter Longo, a renowned expert in aging and longevity.
“This is the first study to show that a food-based intervention that does not require chronic dietary or other lifestyle changes can make people biologically younger,” said Longo. The study analyzed the effects of the FMD on two groups of participants, each consisting of men and women between the ages of 18 and 70.
The participants who followed the FMD underwent 3-4 monthly cycles, adhering to the diet for five days and then returning to their normal eating habits for the remaining 25 days. The control groups were instructed to follow either a normal or Mediterranean-style diet.
The results were astounding. Participants in the FMD group experienced lower diabetes risk factors, including reduced insulin resistance and lower HbA1c levels. Magnetic resonance imaging also revealed a decrease in abdominal fat and fat within the liver, indicating a reduced risk of metabolic syndrome.
Furthermore, the FMD cycles appeared to rejuvenate the immune system, as indicated by an increase in the lymphoid-to-myeloid ratio. This ratio is an indicator of a more youthful immune system. Statistical analysis of the results showed that participants in the FMD group reduced their biological age by an average of 2.5 years.
“These findings should encourage healthcare professionals to recommend FMD cycles to patients with higher disease risk factors, as well as the general population interested in improved health and a more youthful age,” said Longo.
The study not only provides evidence for the effectiveness of the FMD in reducing biological aging but also highlights its potential as a short-term dietary intervention that can improve overall health without requiring extensive lifestyle changes.
Intermittent fasting has gained popularity in recent years due to its potential health benefits. Previous research led by Professor Longo has shown that intermittent fasting can lower the risk factors for cancer, diabetes, heart disease, and other age-related diseases in humans. The current study further solidifies the positive effects of intermittent fasting on the immune system and overall biological aging.
As more healthcare professionals become aware of the benefits of intermittent fasting, it is likely that the FMD will become a recommended dietary intervention for individuals looking to improve their health and reduce their disease risk. With its simplicity and effectiveness, intermittent fasting may just be the key to a longer, healthier life.
