(Seoul = Yonhap News) Reporter Han Seong-gan = Research has shown that patients with inflammatory bowel disease (IBD) increasingly use a variety of prescription drugs in the 10 years before diagnosis.
Inflammatory bowel disease is a chronic, incurable intestinal disease that causes multiple ulcers, bleeding, diarrhea, and abdominal pain in the intestinal mucosa when the immune system mistakenly targets and attacks the large intestine (ulcerative colitis) or mainly the small intestine (Crohn’s disease). Remission and recurrence occur repeatedly.
A research team led by Professor Linea Bonfils of the Molecular Prediction Center for Inflammatory Bowel Diseases (PREDICT), Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark, analyzed the medical records of 29,219 people diagnosed with inflammatory bowel disease between 2005 and 2018 for the 10 years before diagnosis. As a result, this fact was revealed, HealthDay News reported on the 22nd.
The research team compared and analyzed these medical records with the medical records of the same number of control groups without IBD who were matched for gender and age.
The research team found that the IBD group had a prescription rate of 12 of the 14 main groups of the World Health Organization’s (WHO) Drug Classification Code (ATC) drugs in the 10 years before diagnosis, which was 1.1 to 1.8 times higher than that of the control group.
In particular, the IBD group saw a sharp rise in prescription rates for medications used to treat lesions in various organs of the body in the two years before diagnosis.
For example, in the 10 years before diagnosis, the IBD group was 2.7 times more likely to be prescribed immunosuppressants, 2.3 times more likely to be prescribed anemia medications, and 1.9 times more likely to be prescribed analgesics and psychotropic drugs than the control group.
This trend was the same regardless of age, gender, Crohn’s disease, and ulcerative colitis, but was most noticeable in Crohn’s disease.
The research team explained that the fact that prescription medication administration increased so many years before IBD diagnosis suggests that IBD is a disease that is associated with multiple organs in the body.
The results of this study were published in the latest issue of the American Journal of Gastroenterology, an academic journal of the American College of Gastroenterology (ACG).
skhan@yna.co.kr
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2024-01-23 22:22:00
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