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Bambang also appealed to the public not to panic excessively about mutations, such as D614G. “However, we must remain fully vigilant and disciplined in carrying out health protocols to prevent transmission of Covid-19,” suggested Bambang.
Head of the Eijkman Institute for Molecular Biology, Amin Soebandrio, confirmed this. Amin explained that this virus mutation does not change the structure or function of the receptor-binding domain (RBD) which is responsible for infecting parts of human protein.
Amin added that the performance of the vaccine will not be affected, as long as the vaccine is aimed at RBD, which is part of the spike virus that is the target of the vaccine. “Although changes occur in protein spikes, but at a different location. So that the RBD is not disturbed, as long as the vaccine is intended to have RBD, it will not interfere with the performance of the vaccine, ”Amin claims.
Amin claimed that Indonesia had sent 24 samples of the SARS-CoV-2 genome virus or whole genome sequencing (WGS) to the global GISAID institute. Of the 24 genomic virus samples, nine of them contained the D614G mutation.
The details, two from Surabaya, three from Yogyakarta, two from Tangerang and Jakarta, and two from Bandung. In fact, it was previously discovered in Germany and China in January 2020.
On the other hand, the Chair of the Research and Innovation Consortium on COVID-19, Prof. Ali Ghufron Mukti, said that there was no evidence that the D614G mutation was more infectious or more dangerous. “What needs attention is the L18F mutation that has antibody access,” he said. (Also read: Positive Covid-19 Record in the City of Bogor, 30 people increase a day and 2 die)
(iqb)
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