I study[Cancer Killer]notes that cancer risk for men is higher than risk reduction for women – Hong Kong Economic Times – TOPick – Health – Health Information

Cancer is the number one killer in Hong Kong, accounting for 29.2% of all deaths recorded in 2020. According to a study in Cancer, a journal of the American Cancer Society, men have a higher risk of developing cancer than to women, probably due to biological sex differences.

The National Cancer Institute team evaluated the difference in cancer risk between 1995 and 2011 for nearly 300,000 participants in the American Institute of Retired Persons (NIH-AARP) Diet and Health Study, 171,274 men and 171,274 women There were 122,826 people between the ages of 50 and 71.

During this period, there were 17,951 new cases of cancer in men and 8,742 in women. The research team collected data on 21 cancer sites. Among them, thyroid cancer and gallbladder cancer are mostly female patients. As with other cancers, the incidence rate of males is 1.3 to 10.8 times that of females.

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The research team also analyzed risk factors for smoking, alcohol consumption, diet, physical activity and medical history and found that these risk factors account for only a small fraction of most cases of cancer in men, reflecting that gender differences in the incidence of most cancers still exist.

For example, elevated testosterone levels in men are associated with susceptibility to skin cancer and liver cancer; whereas women’s immunological responses such as “Th2” in T helper lymphocytes can reduce cancer susceptibility and reduce the risk of liver and oropharynx cancer.

The results suggest that biological differences between the sexes, such as physiology, immunity, genetics, etc., play an important role in the susceptibility of men and women to cancer. The realization of precision medicine through translational clinical research should reduce and eliminate gender disparities in cancer.

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Responsible editor: Luo Jiaxin