At the event “MP GROUP GENOMIC HEALTH AND WELLNESS” organized by MP Group (Thailand) Company Limited to launch innovative technology, genomics and genes testing that play a huge role and importance in medicine, by Prof. Clinic Emeritus. Dr. Wittaya Thithaphan, President of the Royal College of Obstetricians and Gynecologists of Thailand, gave a special lecture on “MEDICAL INSIGHTS INTO HPV: FINDING HPV = STOP CERVICAL CANCER”. Cervical cancerIt is caused by infection with the human papillomavirus (HPV). There are 14 strains that cause disease.
When HPV enters the body through sexual intercourse. If a blood vessel is torn, blood can enter. and rushes to the cells below, capturing the surface of the cervix The virus fuses with the nuclear cell and replicates. make cells distorted In which 80-90% of people infected with HP do not develop cancer, approximately 10% develop cancer. If the distance into the blood lymph nodes spread throughout the body and cause death
“Once there is an infection, it is not possible to tell which people will develop cancer or who will not. From normal cells to aggressive cancers. Spread throughout the body takes approximately 10-15 years before there are no symptoms. This is cruelty. But if the distance spreads If there is bleeding when having sex White discharge with a putrid smell makes you wonder if it is or not. which can be prevented by vaccination Frequent screening, check every year. If it’s the case, it’s found quickly, treated quickly, cured, but when it’s in the final stages, death occurs,” said Clinical Professor Emeritus Dr. Witthaya.
Can be detected even before infection.
How to screen for HPV with HPV DNA Self-sampling It is a genetic test for the HPV virus. Women can self-collect a cervical specimen. No need to be examined by a doctor No need to climb the trestle So don’t be shy. Don’t be afraid of getting hurt. There is time to check. This can be done by inserting the tip into the vagina with the tip of the container against the wall and rotating. Pull it out and put it in the test kit and send it to the staff to take it to the science laboratory for testing.
“Research has been done on patients. More than 5,000 cases have been found. It is private and 96% of the results can be read. The Royal College of Obstetrics therefore has a policy to stop screening with Pap smears. But check using the HPV DNA Self-sampling method because it is more sensitive, knowing from the time of infection but not yet cancer. Currently, the National Health Security Office (NHSO) supports free testing for all women in the target group. While some people with the disease cost more than 1 million baht to treat, the screening fee is about 50 baht. ”Clinical Professor Emeritus Dr. Witthaya said.
Cancer is the 3rd leading cause of death among Thai women.
For in Thailand About 7.45 Thai women die from cervical cancer per 100,000 population. It is the third leading cause of death from cancer, while the World Health Organization Globally, by 2030, 90% of children under 15 years of age must be vaccinated, 70% of women aged 35-45 years must receive an HPV test, 90% of people with early stage cancer must be cured, and 90% of women with cancer must be cured. Less than 4 per 100,000 population
However, if Thailand has screening with HPV DNA Self-sampling It will also make you aware of the strains that many Thai people are infected with. This information can be used to develop a vaccine to prevent cervical cancer that is especially suitable for Thai people and people in this region. It will help reduce morbidity and death rates even more.
HPV Organization The Toilab
Notaphon Bunbubpha, Chairman of the Executive Board of MP Group (Thailand) Company Limited, said that if one cervical cancer can be eliminated, it will greatly create sustainability for the health of the country. MP Group therefore would like to invite partners in the public health network. Both public and private organizations join the project, mission to conquer cervical cancer (HPV zero case), screening using the HPV DNA Test, identifying 14 high-risk strains. By collecting samples manually Self-Sampling Kit
By driving “HPV The Toilab” organization to campaign for cervical cancer screening in the organization. To women who are the main force of the organization By using the HPV DNA Self-sampling test kit. Put it in the HR department Then have an employee pick you up and check yourself. Easy access. Just pick up the test kit and go to the bathroom. Collect samples manually Return it to the HR department for forwarding to the lab. Can detect all 14 species.
“The test results will tell whether or not you have been infected with HPV. Infected strains and the concentration of strains detected If you don’t have cancer, you won’t be alarmed and then get screened again the following year to see if the infected cells have developed or not. Able to know risks leading to cancer prevention If it is, you will find it quickly. Leads to faster treatment completely cured,” said Nathaporn.
Reduce personnel losses
Benefits that organizations will receive from this project include: 1. Employees of the organization will have free access to rights. of the government sector’s cervical cancer screening. 2. The organization can plan the prevention of cervical cancer from the HPV pathogen. 3. Reduce the loss of organizational personnel from cervical cancer and 4. Promote the health of personnel in the organization. Helps improve the quality of life of personnel Free from cervical cancer
As for HPV DNA Self-sampling technology, it can detect 14 strains that are at high risk of causing cancer, including being used to monitor cases of HPV infection. same species repeated The body is unable to eliminate the infection on its own, increasing the risk of cancer. ,Can identify the severity of virus infection in all strains. ,indicates the amount of infection in cases of co-infection with multiple strains. ,Report results quickly and support large-scale screening with an accurate and accurate AI test result analysis system. and leads to calculating the prevalence rate of HPV strains in Thailand.
“Genomics” checks genes – prevents disease
Prof. Emeritus Dr. Kasem Wattanachai, Privy Councilor, said in presiding over the opening ceremony and giving a special lecture on “GENOMIC HEALTH AND WELLNESS” that there are 4 goals of medicine: 1. Reduction of risks 2. Prevention of disease ( Prevention of diseases) 3.Treatment of illness
and 4. Prognosis (Prediction of outcome). In the past, doctors would assume that a group of patients with this disease This medicine must be given. The patient’s genetic code was never discussed. Because I thought the medicine had already taken care of it. But today we know that the genetic code divides patients even further. Not just a diabetic patient or just cancer
With consideration to personal medicine (Personalized medicine), which must have technology that can detect quickly and accurately. Able to know in depth the genetic code of each patient Can tell whether it will be this disease or not. How should it be treated? And how much will it be cured after treatment? and precision medicine
which covers a broader meaning than health But it includes the topic of Wellness (wellness) or health. Not specific to one person But it refers to the whole matter of genomics. Environment and lifestyle These affect all health. It is a guideline of medicine. Health and wellness today and tomorrow to be healthy Live long happily
such as South Korea The genome is used To predict who will have what disease If it is, then use genetic knowledge to find the best treatment, select medicine, check for drug allergies, and use medicine as appropriate for each individual. This is not to say that 2 million people have this disease and all use the same treatment. Because of current genome technology Patients can be separated into deeper subgroups. and choose the best treatment method and can predict who will recover and how much
Check genes to know your risk of breast cancer.
One example of genetic testing that Thailand offers and is a free benefit for all Thai people is testing for the BRCA1/BRCA2 mutation gene. It will indicate the chance that a person with a positive result will develop breast or ovarian cancer in the future.
Dr. Phasakorn Wanchaijirabon Assistant Director of the Center for Advanced Cancer Expertise Prapokklao Hospital Chanthaburi said that in 2040, cancer patients around the world will increase. Most of them will be Asian people, from 5% to 8.79%, which currently has the highest prevalence of breast cancer in the world, but by 2070, colon and rectal cancer will exceed breast cancer.
for Thailand Cancers that will be found more frequently include breast, colon and rectal, prostate, and lung cancers, with cervical cancer. Stomach cancer will decrease and cancer will be the number 1 cause of premature death in people under 70 years of age.
One of the causes of cancer is mutation mechanisms. The BRCA1/BRCA2 mutation gene test Can be checked both for prevention If detected, it is considered that there is a risk of breast cancer. This will allow you to take steps to prevent yourself from getting the disease. For example, if it is detected in one breast, There is a 3.7 times risk of breast cancer on the other side, so the other breast should be removed.
Including removing the ovaries at the right time and cut the uterus as well and for treatment There are targeted medicines. It will focus on the abnormal BRCA gene. Therefore, in breast cancer patients who have this gene detected, they can use targeted drugs for treatment. However, the process before testing must evaluate 4 factors: the right person, the right reason, the right method, and the results are interpreted.
“Gene testing is the point of confirming whether there is a risk of cancer or not. If you know in advance that you are at risk of having breast cancer or colon cancer. It will prevent us from getting cancer, like Ms. Angelena Jolie who had her breasts and ovaries removed. This makes him not have to worry about having these two types of cancer because throughout his life if it is not removed there will be a risk of getting it up to 87%,” said Dr. Phasakorn.
Currently, 2 target groups are entitled to free BRCA1/BRCA2 gene testing, including high-risk breast cancer patients and direct relatives of fathers, mothers, siblings, and children of breast cancer patients who have been diagnosed with abnormalities in this gene.
MP Group’s role and commitment
Nathaporn provided additional information. Testing for genes related to disease Because it will show that the genes are normal. Or when the gene changes, it will cause disease or appear to cause disease. The genes that cause disease have 2 parts: genetics received from parents. And from the abnormal DNA replication process, organ abnormalities will occur.
Testing method with Next Generation Sequencing (NGS) technology is a technique for sequencing genetic material. To detect changes in genes of interest Can detect more than 1 gene mutation per analysis. Suitable for predicting cancer risk. Cancer diagnosis Including selecting the appropriate medication for each individual’s treatment.
Divided into branches of testing: 1. Cancer, checking for mutated genes that cause cancer. To lead to targeted treatment called Personalized Precision Medicine
2.Wellness: Check for risk of genetic diseases such as cardiovascular disease, Alzheimer’s disease. Parkinson’s disease
3. Find the type and amount of all bacteria in the intestines that affect health and lead to a balance of microorganisms called probiotics.
4. Check for drug resistance genes The amount of medicine that should be given, such as anticonvulsants, gas drugs related to the function of the HLA gene, and 5.Lifespan It is a plan to change your lifestyle to suit your age. To promote quality of life for a longer life.
For example, the Health Risks Advance genetic testing program is a screening program for cancer and inherited diseases. To indicate the level of risk for various diseases covering the entire body. Such as 14 types of cancer in women and men, stroke, Parkinson’s, Alzheimer’s, coronary artery disease, etc.
The wellness genechecks genetic testing program will help you plan your life with Health solutions to change your lifestyle. Helps reduce the chance or prevent serious diseases. or various illnesses that may occur in the future. In addition, there is a gas allergy gene test kit. Allergic to HIV antiretroviral drugs, allergic to anticonvulsant drugs, and counseling services are also available.
While Ritthichai Sriwijarn, Chairman of the Board of Directors of MP Group (Thailand) Company Limited, said that the company has been in business for 23 years since 2001, being an expert in medical diagnosis, importing, distributing, producing and exporting diagnostic test kits. Meets world-class standards It is considered one of the important escapes that have always been developed. There are customer groups including the public sector, private sector, hospitals, clinics, pharmacies, stores, and the general public.
The company is ready to further develop the organization towards success in the future with modern testing innovations. Supports modern medicine to provide universal access to services, attention to standards, prompt service, fast and accurate results. Leading to a sustainable quality of life for Thai people.
2024-01-22 04:37:00
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