The coronavirus mainly causes respiratory problemsHowever, it affects other organs and systems of the body. In this context, an investigation carried out in the United Kingdom and published in the journal The BMJ, evidence that one in three patients discharged from hospital, after contagion with Covid-19, readmission before 7 months and with higher rates of multi-organ damage.
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To understand the phenomenon of Covid persistente (‘long Covid’) the team of researchers from the UK Office for National Statistics, University College London and the University of Leicester compared the Organ dysfunction rates in individuals with symptoms after infection with the virus several months after hospital discharge, with a matched control group of the general population.
The sample featured 47,780 participants, with an average age of 65 years hospitalized in England infected by Covid who were discharged before August 31, 2020. To monitor the rates of readmission to the hospital, health records were used, death from any cause and disease diagnoses respiratory, cardiovascular, metabolic, kidney and liver until September 30, 2020.
The mean follow-up was 140 days. The study registry found that almost a third of the individuals who were discharged from the hospital after acute Covid were readmitted (14,060 of 47,780) and more than 1 in 10 (5.875) died after discharge.
“These events occurred in rates of 766 readmissions and 320 deaths per 1,000 person-years, which were four and eight times higher, respectively, than those of matched controls, “the study authors explain.
Increase in diseases after the virus
The respiratory, cardiovascular diseases and diabetes They also increased significantly in patients infected with the virus, with 539, 66 and 29 new diagnoses per 1,000 person-years, respectively (equivalent to 27, three and 1.5 times more than in matched controls).
Differences in multiorgan dysfunction between Covid patients and matched controls were greater for women. people under age 70 than for those age 70 and over, and in minority ethnic groups compared to the white population, with the largest differences observed for respiratory disease. Differences in disease rates between men and women they were generally small.
“Our findings suggest that the diagnosis, treatment, and prevention of postcovid syndrome require integrated approaches rather than specific to each organ or disease,” the research authors note.
The researchers further suggest that an “urgent” study is needed to understand the risk factors for persistent covid syndrome, so that the treatment can better target populations at risk from a demographic and clinical point of view.
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