Honeybees and other pollinators produce enzymes that detoxify defense chemicals from plants, such as alkaloids found in their nectar and pollen, according to a study by the University of Exeter and Bayer AG. The research examined several species in a group called Hymenoptera and discovered that they all produce the same group of enzymes to tackle alkaloid toxins. Understanding how insects react to specific toxins can inform future production of pesticides and insecticides, according to Dr. Bartek Troczka from the University of Exeter. The paper was published in the journal Science Advances.

Pollination is an essential ecosystem service responsible for the reproduction of flowering plants, which provide food, shelter, and habitat for various animals, including humans. However, it is not just a simple mechanism of transferring pollen from one flower to another; it is an intricate process that involves interactions between pollinators and plants. Plants produce a lot of defensive chemicals to protect themselves from herbivores and pathogens, including toxins that can be harmful to pollinators. But how do pollinators cope with these plant toxins? A recent study sheds light on this question and reveals that pollinators have evolved various strategies to deal with toxic plant chemicals. This article will discuss the study’s findings and their implications for understanding the complex relationship between plants and pollinators.


New research has highlighted the unique abilities of pollinators such as honeybees to produce enzymes that can detoxify defense chemicals produced by plants. Many plants produce alkaloids as a form of protection against herbivores, and these toxins are also found in their nectar and pollen. The study, conducted by the University of Exeter and Bayer AG, examined the genetic composition of several species in the Hymenoptera group, which encompasses bees, wasps, ants, and sawflies that share a common ancestor about 280 million years ago. It found that all the species tested shared the same group of enzymes (the CYP336 family of cytochrome P450 enzymes) that can combat alkaloid toxins.

Remarkably, even though these species differ greatly, they all retain the ability to detoxify alkaloids. The research suggests that this family of genes has been preserved across almost 300 million years of evolution by a whole order of insects with very diverse lifestyles. Although some of these species have very little contact with certain key alkaloids, such as nicotine, they appear to have retained the ability to metabolize them as an aspect of their genetic heritage, much like the human tailbone or appendix. The study examined the genomes of key hymenopteran species, as well as extracting the enzymes produced by these species and placing them in a cell line to see how they would react with alkaloids. The researchers found that the enzymes do indeed detoxify the toxins.

Understanding how insects react to specific toxins is vital in the production of new chemicals such as pesticides and insecticides. To avoid environmental damage, researchers need specific compounds that will do specific things. The study feeds into the wider attempt to understand how chemicals are broken down by insects and to what extent the responsible genes persist across insect groups. The paper published in the journal Science Advances highlights the promise of multidisciplinary teamwork to better understand the molecular and evolutionary basis of detoxification mechanisms in insects, which will ultimately aid in the understanding of their interaction with other toxins, including insecticides. This study provides valuable insights into how pollinators face and overcome the challenges of dealing with toxins in their environment.


In conclusion, the study on how pollinators cope with plant toxins is a significant step forward in understanding the intricate relationship between plants and their animal counterparts. By shedding light on the various ways by which pollinators evade harmful plant substances, researchers have opened doors to further investigations on this subject. With the threat of climate change and habitat loss looming large, it is essential to comprehend the intricacies of ecosystems more deeply. Only then can we hope to create sustainable and eco-friendly solutions to protect our environment- and the animals that call it home.