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Higher Levels of Inflammatory Bacteria Linked to Accelerated Ageing and Fitness Decline: New Research Reveals

New research conducted by a team at the Hungarian University of Sports Science suggests that higher levels of inflammatory bacteria in the gut are linked to accelerated aging and poorer fitness performance. The study, published in the journal of Developmental Cognitive Neuroscience, highlights the importance of gut microbiome diversity in maintaining overall health and longevity.

The researchers examined the relationship between gut microbiome diversity, biological age, and physical fitness in 80 amateur rowers. Each participant underwent fitness assessments and provided stool and blood samples for analysis. The analysis focused on epigenetic markers, which are switches in our DNA that control gene expression and play a role in cellular development and aging.

The findings revealed that individuals with higher levels of inflammatory bacteria experienced accelerated aging, meaning they appeared older than their chronological age. On the other hand, those with higher levels of anti-inflammatory bacteria had improved fitness indicators and a slower rate of aging. The presence of inflammatory bacteria was also associated with poorer performance in fitness tests.

These results challenge the common assumption that more bacteria in the gut equates to better health. The study did not establish a cause-and-effect relationship, but it is possible that the athletes’ healthier dietary choices influenced the abundance of beneficial bacteria in their gut.

Professor Zsolt Radak, lead author of the study, emphasized the importance of identifying these relationships and potentially modifying the abundance of inflammatory bacteria to slow down the aging process and promote a healthier life. The team is currently conducting a follow-up study where they are altering the rowers’ gut microbiome using probiotics to assess the direct impact on biological age.

In addition, the researchers are working on a separate study involving 60 Olympic champions between the ages of 25 and 102. This study aims to explore the impact of early high-level physical activity on the aging process. Preliminary results have already shown that elite athletes have a younger epigenetic age compared to their chronological age.

These findings open up new possibilities for utilizing probiotics and modifying the gut microbiome to promote health, longevity, and improved fitness performance. The results of the follow-up study and the study involving Olympic champions are expected to provide further insights into the role of gut bacteria in the aging process.
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How does the diversity of gut microbiome affect aging and fitness performance?

New research conducted by a team at the Hungarian University of Sports Science suggests that the bacteria in our gut may play a significant role in how we age and our fitness performance. This study, published in the journal of Developmental Cognitive Neuroscience, highlights the importance of having a diverse gut microbiome for overall health and longevity.

To investigate this relationship, the researchers examined 80 amateur rowers and analyzed their gut microbiome diversity, biological age, and physical fitness. The participants underwent fitness assessments and provided stool and blood samples for analysis. The focus was on epigenetic markers, or switches in our DNA that control gene expression and influence cellular development and aging.

The findings of the study revealed that individuals with higher levels of inflammatory bacteria in their gut experienced accelerated aging, making them appear older than their actual age. Conversely, those with higher levels of anti-inflammatory bacteria had improved fitness indicators and a slower rate of aging. The presence of inflammatory bacteria was also associated with poorer performance in fitness tests.

These results challenge the common belief that more bacteria in the gut automatically equates to better health. It should be noted that the study did not establish a cause-and-effect relationship, but it is possible that the rowers’ healthier dietary choices influenced the abundance of beneficial bacteria in their gut.

Professor Zsolt Radak, the lead author of the study, emphasized the importance of understanding these relationships and potentially modifying the abundance of inflammatory bacteria to slow down the aging process and promote a healthier life. The team is currently conducting a follow-up study where they are using probiotics to alter the rowers’ gut microbiome and assess the direct impact on biological age.

Additionally, the researchers are working on a separate study involving 60 Olympic champions between the ages of 25 and 102. This study aims to explore the impact of early high-level physical activity on the aging process. Preliminary results have already shown that elite athletes have a younger epigenetic age compared to their chronological age.

These findings open up exciting possibilities for using probiotics and modifying the gut microbiome to promote health, longevity, and improved fitness performance. The results of the follow-up study and the study involving Olympic champions are expected to provide further insights into the role of gut bacteria in the aging process.

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