Head and neck cancer affects the moist and mucosal surfaces in the head and neck, including the mouth, nose, and throat. Early detection is imperative for successful treatment of this type of cancer. It usually originates in squamous cells and is also known as squamous cell cancer. Symptoms may include change in voice, difficulty eating or swallowing, and nosebleeds. A biopsy or subsequent CT scan and MRI may be required if anything suspicious is found. Several screening and diagnostic tests are available for early detection. Early diagnosis of cancer reduces the need for extensive treatment, and delay in treatment increases the chances of organ removal, disability, and deformity. Raising awareness about head and neck cancer is crucial to promoting early detection and treatment. Lip and tongue cancer treatment requires specialization to maintain its cure.