GLP-1 receptor agonist drug class, efficient in weight reduction earlier than bariatric surgical procedure

▲ Analysis outcomes have proven that using GLP-1 receptor antagonist medication earlier than bariatric surgical procedure is efficient in decreasing weight earlier than surgical procedure. (Picture = DB)

[메디컬투데이=이승재 기자] Analysis outcomes have proven that using GLP-1 receptor antagonist medication earlier than bariatric surgical procedure is efficient in decreasing weight earlier than surgical procedure.

The outcomes of a research inspecting the impact of GLP-1 receptor antagonist medication on weight reduction earlier than bariatric surgical procedure have been offered on the 2024 annual assembly of the American Society for Metabolic and Bariatric Surgical procedure.

In keeping with the US Facilities for Illness Management and Prevention (CDC), overweight adults within the US make up 42% of the overall grownup inhabitants. If you’re obese, your immune system is weakened and broken and continual irritation happens, which might trigger issues corresponding to heart problems, stroke, sort 2 diabetes, and most cancers.

Lately, bariatric surgical procedure has been actively carried out to forestall these issues and cut back weight. Bariatric surgical procedure is indicated for sufferers with extreme or reasonable weight problems and metabolic issues corresponding to diabetes. In 2022, roughly 280,000 bariatric surgical procedures will probably be carried out in america.

Most sufferers scheduled for bariatric surgical procedure are suggested to drop some weight, as weight problems itself will increase the danger of the surgical procedure going flawed.

There are alternative ways to drop some weight, together with weight-reduction plan, train, and drugs. Amongst them, when medication of the category ‘GLP-1 receptor agonist’ corresponding to ‘Ozempic’ have been launched, many makes an attempt have been made not too long ago to drop some weight through the use of medication.

The researchers studied the impact of weight reduction with a category of medication ‘GLP-1 receptor agonist’ earlier than bariatric surgical procedure in 113 sufferers who underwent bariatric surgical procedure.

70 of the sufferers tried to drop some weight earlier than the surgical procedure, and the strategies included strategies corresponding to weight-reduction plan and train with out medication, strategies utilizing one sort of GLP-1 receptor agonist drug class , and strategies utilizing two or extra forms of GLP-1 receptors There was a technique utilizing agonist-based medication.

The outcomes of the research confirmed that the tactic of utilizing two or extra forms of remedy had the perfect impact on weight reduction, with a mean diminished price of 13% over 6 to 12 months. When it comes to utilizing one sort of drugs, the load loss price was the second greatest at 8%, and when it comes to weight-reduction plan and train, it was the bottom at 6%.

Primarily based on these findings, the researchers concluded that using GLP-1 receptor antagonist medication earlier than bariatric surgical procedure is efficient in decreasing weight earlier than surgical procedure.

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