Genetic Link Between Blood Cancer and Rheumatoid Arthritis Revealed by American Scientists

A form of rheumatoid arthritis is caused by the same genetic mutation that causes blood cancer. Therefore, medications that are prescribed for patients with blood cancer can be effective for arthritis. American scientists told this.

“These results are only the tip of the iceberg that we are seeing between autoimmune diseases and blood cancer. Medicines commonly prescribed to patients with blood cancer may also be effective for some types of arthritis,” the scientists said. transmitting Blood journal.

The seronegative subtype of rheumatoid arthritis, unlike other forms of the disease, cannot be detected using a standard blood test. As scientists have discovered, most patients with blood cancer (myelodysplasia and acute myeloid leukemia) have seronegative arthritis. Mutations in the IDH1 and IDH2 genes, which are present in people with blood cancer, can cause inflammation, according to the analysis. These mutations lead to the development of arthritis.

To detect cancer in the early stages, it is necessary to do an annual medical examination, says the chief physician of the MAMMA clinic, oncologist, oncosurgeon, chemotherapist, candidate of medical sciences Anton Ivanov. A complete blood count will help determine normal, low or high levels of different subsets of cells. It is also important to perform a biochemical blood test, which shows the presence of biochemical markers that regulate the functioning of internal organs, writes RT.