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Gene Discovery and Potential Treatment for Obesity-Related Metabolic Problems

Neurogeneticist Bart Dermaut, together with other researchers, has now discovered the link between the error in the gene and the specific obesity problems that also affect less obese people. “It is a very rare condition,” says Dermaut, but this discovery is a new piece of the puzzle to gain knowledge about metabolic problems in obesity, which is a major problem worldwide and is increasing.”

“We now know that the protein in the plate3 gene is crucial for the development of healthy fat tissue. And the error has been found in that gene. So now we can also influence the activity of that gene in the long term with medicines,” explains Dr. Nika Shuermans. “So we hope that in the future we can better protect people with obesity from the metabolic consequences. This concerns diabetes, fatty liver disease and high cholesterol, which we may be able to treat better. We are not going to prevent diabetes by doing this, but we have Now we have a lever with which we can possibly reduce susceptibility to diabetes,” concludes Schuermans.

2023-11-03 15:47:00
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