TEMPO.CO, Jakarta – Preliminary research on safety side effects the COVID-19 vaccine from Pfizer and Moderna is not final. However, overall the Pfizer vaccine is said to be safe, as is the Moderna vaccine which shows no serious safety issues.
However, like any other vaccination, you can experience some side effects from the COVID-19 vaccine. The Centers for Disease Control and Prevention (CDC) say the effects include pain and swelling at the injection site, fever, chills, fatigue, and headaches.
“Other side effects of the COVID-19 vaccine may include muscle aches and joint pain. From what we know, most of the side effects will likely appear within the first day or two of receiving the vaccine, but may potentially appear later,” said the vice president. pharmacy programs and diagnostic services at ZOOM + Care, Thad Mick, as quoted from Shape.
If these side effects are said to be very similar to the symptoms of COVID-19, that’s because they basically are. Vaccine it stimulates the immune system to fight off the virus, according to California pediatrician Richard Pan.
He emphasized that this does not mean the COVID-19 vaccine can cause COVID-19 because the mRNA from the vaccine does not permanently affect cells. Instead, the mRNA is just a temporary blueprint for protein spikes that lie on the surface of the virus.
“This blueprint is very fragile, therefore vaccines must be stored in very cold temperatures before use,” said Pan.
The body eventually removes the blueprint after being vaccinated. However, the antibodies developed in response will remain. The CDC says more data is needed to confirm how long the antibodies built from the COVID-19 vaccine will last.
Then, how common are the side effects of the COVID-19 vaccine? The United States Food and Drug Administration (FDA) is still evaluating data on how common the COVID-19 side effects might be in the general population.
Pan said for now information from Pfizer and Moderna about large-scale clinical trials suggests a small number of people will experience significant but temporary symptoms after receiving the vaccine. COVID-19.
The Moderna trial showed as many as 2.7 percent of people experienced pain at the injection site after the first dose. After a second dose given four weeks after the first injection, about 9.7 percent of people experienced fatigue.
Additionally, 8.9 percent reported muscle pain, 5.2 percent experienced joint pain, 4.5 percent reported headache, 4.1 percent experienced pain, and 2 percent experienced redness at the injection site.
This effect is not much different from Pfizer’s COVID-19 vaccine. Trial results showed as many as 3.8 percent of people reported fatigue and 2 percent experienced headaches after the second dose given three weeks after the first injection.
Less than 1 percent of people in clinical trials reported fever and a small number of test participants, 0.3 percent, also reported swollen lymph nodes that generally resolved within 10 days of vaccination. According to Pan, while these side effects are temporary and appear less common, they could be significant enough that some people may need to skip a day of work after being vaccinated.
Apart from these effects, there are also concerns about an allergic reaction to Pfizer’s COVID-19 vaccine. In this regard, the FDA states that individuals with a history of severe allergic reactions, such as anaphylaxis should not be vaccinated in the past.
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