Ebola can hide in the brain for years after an infection

[EN VIDÉO] Interview 4/5: Understanding the Ebola virus The Ebola virus acts spectacularly. The infection causes an acute viral haemorrhagic fever which kills in nearly 90% of cases. We met Jean-François Saluzzo, virologist with the WHO, so that he could tell us about the conditions of transmission and the symptoms linked to this virus originating in Africa.

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In an experiment conducted on Origin of primates
The debate remains…” data-image=”https://cdn.futura-sciences.com/buildsv6/images/midioriginal/4/0/f/40f01b0d93_52778_japanese-macaque-udon-fotopedia-cc-nc-20. jpg” data-url=”https://www.futura-sciences.com/planete/definitions/zoology-primate-2141/” data-more=”Read more”>primates non-humans, theU.S. Army Medical Research Institute of Infectious Disease demonstrated the ability of virus Ebola to hide in the brain for years.

« We observed that approximately 20% of monkeys that survived a lethal dose of Ebola virus after treatment withmonoclonal antibodies always show persistent infection – specifically in the ventricular system of the brain in which the liquid cerebrospinal is produced and circulates – and even when Ebola has been cleared from other organs », explains Xiankun Zen, director of the study published in Science Translational Medecine. The case of two monkeys is particularly worrying. The animals survived the initial infection, but eventually died from a resurgence of the disease.

Ebola persisted in the brains of monkeys treated with monoclonal antibodies

The persistent presence of the Ebola virus in the brain induced the death of ependymocytes – a family of cells that form part of the blood-brain barrier of the choroid plexus. A inflammation Severe localization ensued and the virus spread throughout the ventricular system of the brain causing animal death. The Ebola virus can also hide in humans.

In 2021, scientists analyzed the case of a man in whom the virus lay dormant for five years in his Testicular function
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