Reporter Huang Yunhan / full report
There are more than 1 kg of bacteria in the human body that coexist with the host in the intestinal tract. Depending on factors such as age, dietary habits, metabolism, geography, antibiotic intake and stress, these bacteria also co-evolve with the host and influenza Our immunity, cancer and diseases such as mental and neurodegenerative diseases, even determine the “body” of each of us. Another study pointed out that “mothers who eat less dietary fiber are more likely to gain weight in their children”
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Regarding the correlation between intestinal bacteria and obesity, according to the article “The intestinal microbiota and obesity: from correlation to causality” in “Nature”, it is emphasized that through diet management improves the richness of the intestinal microbiota and reduces the body weight.
In the study, mice that underwent cesarean sections were kept in a sterile environment. Once the gut bacteria were infused, the mice’s body weight increased by 60% and insulin sensitivity also decreased. Or the gut bacteria of skinny mice, the mice that were eventually planted with “fat mouse bacteria” actually gained more fat than the mice that were planted with “skinny mouse bacteria.”
Next, the research hopes to go further to explore whether “fat people’s eating habits” have developed “fatty bacteria” or “genes” are at work. The answer is that both are involved. In November 2016, “Nature Microbiology” pointed out that it is currently known that a high-fat diet can cause imbalance of intestinal flora, chronic inflammation and obesity. Furthermore, it was also found that mice after inhibiting the expression of the “gene dusp6 of the dual specificity of dephosphatase” not only did not become obese after eating high-fat food, but also the intestinal bacterial phase can be kept constant, and the transfer of fecal bacteria to common voles can also slow down the weight gain of voles common.
The research team also filed a provisional patent application in the United States, hoping to maintain a stable gut flora by regulating expression of the dual-specificity dephosphatase gene dusp6 in the future, which could further help treat obesity and related metabolic diseases. The cultivation method of intestinal bacteria with the effect of inhibiting obesity has been mastered, and the strains are being screened, and the verification of the effect is expected to be completed within 1 to 2 years.
The intestinal flora is one of the keys to weight gain or loss. As mentioned at the outset, if a partial eclipse disrupts the balance of your gut flora, it can compound the impact on your weight. According to “The impact of dietary intervention on the genetic richness of the gut microbiota.”, 49 overweight or obese people were given a low-fat, low-calorie diet high in protein and fiber, and they found that such a diet could really change the composition of the intestinal bacteria of this group of people.
Although the current scale of research is relatively small, they tell us one possibility: Through diet management, the richness of intestinal flora can be improved and weight can be reduced. years of hard research by scientists, it is best to start from the daily intake of dietary fiber recommended by the Ministry of Health and Welfare of 25-35 grams, and replace refined starch, vegetables and fruit with whole grains.579 : Children 5 servings per day, 7 servings for girls, 9 servings for boys.
(Photo / pixabay)
In addition, according to the research paper “Cell Sub-Journal Cell Host & Microbe”, the diet of lactating mothers is a major determinant of the formation of the offspring microbiota, which is closely related to the occurrence of intestinal health, obesity and related diseases in the offspring. Although the nutritional needs of mice and humans are different, it is also a wake-up call for us to pay attention to the importance of food balance when breastfeeding.
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further reading
Drinking water makes you fat it’s true! Study: Gut bacteria determined that the child’s body fat and thin are related to the mother’s diet
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