“Dr. Yong” clarifies the mutated COVID node Destroy more immunity Has reduced the effectiveness of the vaccine
Date 03 Feb. 2021 at 6:13 AM.
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Head of the Center of Specialization in Virology Explains the Node of the Mutant Covid Virus Destroy more immunity May reduce the effectiveness of the vaccine. Yan Thai surveillance
On February 3, 64 Prof. Yong Phoo Worawan, head of the Center of Specialization in Virology. Clinic, Department of Pediatrics Faculty of Medicine Chulalongkorn University In a Facebook post indicating COVID-19 mutation
COVID-19 It’s an RNA virus. Therefore has evolved to change genetics over time
Therefore, mutations of the covid-19 virus are possible.
A virus that started in China And to spread a lot in Europe and America.
The breed has always changed.
A new species that everyone is watching for British breed Also known as B.1.1.7, also known as VOC 202012/01, is Variant of Concern.
Officially announced on December 20 (12) 2020.
This strain has a major amino acid change in position 501, shifting from asparagine to tyrosine, known as N501Y, which is positioned to bind to ACE2 cell receptors, making the virus easier to bind to cells. As a cause for easy infection And spread easily But not about the severity of the disease and the immune system.
Later, there were more mutations than the British breed. Made in south africa The strains are similar to the British strains but with increased mutations in the amino acid location. The protein sprite at 484 was converted from glutamic not to lysine or E484K called B.1.351 or 501Y.V2.
In position 484 it is associated with the immune system. That may affect the effectiveness of the vaccine.
Therefore, special education and surveillance is needed for this breed.
The Brazilian strain found 19 mutations in the Amazon, Brazil, with additional mutations from the British and South African strains at additional 417 locations (K417N / E484K / N501Y), or simply P.1.
Further studies are needed to determine how much this strain will affect the immune system because there is one additional mutation associated with the immune system in that position. 417 The need for genetic code studies to monitor surveillance. And compared with the epidemiology Including the immune system And the severity of the disease It is absolutely necessary and prevents the spread of new species from occurring. In particular, the strains to avoid vaccine immunity. And will reduce the effectiveness of the vaccine
For in Thailand, there has been full surveillance. Especially those who come from abroad, whether from Europe or America.
Currently at the center where I work Monitoring of mutations by testing state quarantine, seven British strains have been identified.
Of the seven, five are from England, one from the United States and one from France.
Foreign species that arise Must be vigilant Not to cause an outbreak in our home
Especially those who come from abroad
And there must be a random inspection of the species that occur in our own home as well. That there are genetic changes So as not to spread rapidly Or vaccine-resistant strains originated in Thailand The importance of studying science for students Therefore it is imperative to understand In this article
#Doctor Yong
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