Sofosbuvir is a hepatitis C drug that can inhibit the development of the virus and repair liver damage. This hepatitis drug works by inhibiting an enzyme that plays a role in the formation of hepatitis C virus RNA. Before taking Sofosbuvir, it is better to understand the following dosage, side effects, and instructions for use.
Quoted from MIMS, the drug Sofosbuvir can make the virus no longer effective in infecting the body. However, this drug cannot prevent transmission of hepatitis C from one person to another.
To be more effective the use of Sofosbuvir is often combined with other antiviral drugs, such as ribavirin, peginterferon, and daclatasvir.
Sofosbuvir must be prescribed by an internist and not used in monotherapy or as a single therapy. So, use it according to the doctor’s directions to avoid side effects.
Dosage of Sofosbuvir
The dosage of Sofosbuvir is adjusted according to the patient’s age, weight (BB), and medical condition. Here is the dosage division for treating hepatitis C:
- Adults: 400 mg once daily, for 12-24 weeks
- Children over 3 years old and weighing under 17 kg: 150 mg once a day
- Children over 3 years old with a weight of 17-35 kg: 200 mg once a day is given
- Children over 3 years old with body weight above 35 kg: 400 mg once a day is given
Side Effects of Sofosbuvir
The use of the drug Sofosbuvir can cause mild side effects such as:
- Diarrhea
- Loss of appetite
- Fatigue
- Trouble sleeping
- Muscle ache
- Headache
In addition, there are a number of serious side effects that can arise from the use of this drug, including:
- Fever
- pale skin
- Shivering
- Swelling of the face
- Dizzy
- Sore throat
- Hard to breathe
- Stupid
Sofosbuvir Interactions with Other Drugs
The use of the drug Sofosbuvir when used together with certain drugs can cause interaction effects, such as:
- When used with phenobarbital, rifampicin, rifabutin, or herbal ingredients such as St. John’s Wort, it can lower levels of the drug Sofosbuvir
- If used with amiodarone, it can cause bradycardia or slow heartbeat
- If used with warfarin, it can increase the risk of poisoning.
Rules for Using Sofosbuvir
Before using Sofosbuvir, follow the doctor’s directions or the instructions listed on the packaging label. Do not reduce or increase the prescribed dose. Do not stop treatment without consulting your doctor, even if you feel better.
This medicine can be taken before or after meals. Take Sofosbuvir with a glass of water without biting or chewing.
If you miss a dose, take it as soon as you remember if the interval with the next consumption is not too close. But if it is close, ignore and do not double the dose of Sofosbuvir.
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