Sunday 17 September 2023, 10.20 a.m.
‘Doctor Teerawat’ points out that a good body alone is not enough. Your brain must be good too. Suggestions on how to ‘age’ like super
17 September 2023 Prof. Dr. Teerawat Hemajutha, Head of the Emerging Disease Health Science Center Faculty of Medicine Chulalongkorn Hospital Posted a message via Facebook “Thirawat Hemachudha Thiravat Hemachudha” as follows…
How to become a super old person
Prof. Dr. Teerawat Haemjutha
A person’s body is just good. It is not enough. The brain must also be good, especially as people get older.
At present, middle-aged people start from the age of 30 to 65, start to age from 65 to 80, and get older (older), that is, over 80 years of age.
At the same time We already know that Dementia, including Alzheimer’s, is important if looking at indicators by examining the brain using nuclear medicine or PET scans. According to educational data from many nationalities, it is found that at the age of 60 years there will be 16% of the amyloid protein that indicates Alzheimer’s. A blood test looks for Tau protein, such as p-Tau 181 or 217, and the value comes back normal. While externally looking at brain activity is still rapid, there is a chance of finding abnormalities from a PET scan. Less than 2% will remain.
However, as age increases The chance of abnormalities in the brain increases regardless of whether symptoms appear or not.
The fact that the outside still looks good even though the inside has abnormalities in the brain Or what we call resilience, it can be explained by replacement work by coordinating nerve connections to be more efficient. This can be analyzed from the activity of nerve fibers using a special electromagnetic computer scan called diffusion tensor imaging.
But at the same time It is still possible that even at age Even at the age of 80 and above, they still have a very active brain. Including atrophy. of the overall brain that is slower, especially the important parts related to movement and memory, and is resistance or has good things that fight against the brain’s degenerative mechanisms.
In-depth analysis of super elderly people Also known as Superager, reported in the journal Lancet Healthy Longev., August 2023, where super-aged people Brain performance is equivalent to or better than that of people aged 50 to 56 years. Long-term follow-up will be followed for another five years.
And when classifying and enumerating lifestyles, behaviors, including 89 other variables, they can be identified. Quite reasonably good though. Being able to move quickly and have regular physical activity. in daily life
And it doesn’t depend on exercising seriously. resulting in super And another thing is that mental health remains good even if you face problems with the death of your life partner or divorce or other problems. You can calm your mind and let go.
This study also examined blood biomarkers using a single molecule assay for the protein.
Amyloidosis, 181 NFL, which reflects brain damage, and GFAP, which indicates inflammation and is a trigger. dementia stages
In the two groups, very elderly people have super brains. with a normal brain There was no difference in these blood results.
But what is clear is that atrophy of the gray matter of the brain, which is the location of the nerve cells Less and slower atrophy in the superbrain, especially in areas related to memory, medial temporal lobe, cholinergic forebrain.
and the part related to movement, motor thalamus
All these things Even though it cannot be specified Elderly people with super brains will have better genetic code than others or not.
But it indicates that the lifestyle behavior is not passive. Deeply fried It doesn’t even have to be cardio or aerobic exercise. It should have the effect of protecting the brain and combining it with a bright mind, not irritated or irritated, even if faced with difficult situations. It will be an important help in keeping the body and brain bright and sustainable and not a burden to society.
But we must not forget that eating food closer to vegetarianism and reducing meat is still important and must be the basis of life.
2023-09-17 03:20:00
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