Certainly! Here is the content you requested:
Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
Table of Contents
-
- Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
- A new study claims fish oil pills slow biological ageing. should we be taking them?
- Daily omega-3 could help prolong health span
- An omega-3 dose a day could slow ageing process, ‘healthspan’ trial finds
- New Findings on Omega-3 Supplements: Can They Slow Biological Aging?
nature.com
A new study claims fish oil pills slow biological ageing. should we be taking them?
Sydney Morning herald
Daily omega-3 could help prolong health span
Medical News Today
An omega-3 dose a day could slow ageing process, ‘healthspan’ trial finds
The Guardian
New Findings on Omega-3 Supplements: Can They Slow Biological Aging?
A groundbreaking study has shown that daily intake of omega-3 fatty acids can have significant effects on the biological aging process, perhaps slowing aging by up to four months. In light of these findings, we sat down with renowned biologist Dr. Heike A. Bischoff-Ferrari to discuss the implications of this research and its relevance to everyday health.
Personalizing Aging with Omega-3 Fatty Acids: An Interview with dr. Heike A. Bischoff-Ferrari
Omega-3 and Biological Aging
Editor: Dr. Bischoff-Ferrari, the recent study you helped lead indicates that omega-3 fatty acids have a protective effect on biological aging.Could you elaborate on these findings?
Bischoff-Ferrari: Certainly! Our study,part of the DO-HEALTH trial,demonstrated that daily intake of one gram of omega-3 can slow down biological aging as measured by DNA methylation clocks. This means that individuals who take omega-3 supplements may experience a delay in aging processes at the molecular level,potentially enhancing their overall healthspan [[1](https://www.news.uzh.ch/en/articles/media/2025/omega-3s-aging-process.html)].
The Role of DNA Methylation
Editor: Your study mentions DNA methylation clocks. How does DNA methylation relate to the aging process?
Bischoff-Ferrari: DNA methylation is a biochemical process that affects gene expression. It becomes progressively altered with aging, and these changes can be used to estimate biological age. our study shows that omega-3 fatty acids influence these epigenetic markers, thus echoes a more youthful biological profile [[2](https://www.sciencedaily.com/releases/2025/02/250204132423.htm)].
Combining Omega-3 with Other Healthy Habits
Editor: What about the combined effects of omega-3 with other factors such as vitamin D and exercise?
Bischoff-Ferrari: Our research indicates that omega-3, vitamin D, and exercise each have individual and additive effects on DNA methylation clocks.Together, they can provide a more comprehensive approach to slowing down biological aging. The effect sizes ranged from 0.16 to 0.32 units, translating to a delay in aging of 2.9 to 3.8 months over three years [[3](https://pubmed.ncbi.nlm.nih.gov/39900648/)].
Practical Applications
Editor: Is there practical advice you’d give to older adults based on these findings?
Bischoff-Ferrari: Absolutely.For older adults, incorporating omega-3 supplements (such as fish oil pills), maintaining an adequate intake of vitamin D, and engaging regularly in physical exercise can contribute to slowing down biological aging. these lifestyle habits can add up to substantial benefits over time and help prolong healthspan [[1](https://www.news.uzh.ch/en/articles/media/2025/omega-3s-aging-process.html)].
Conclusion
Dr. Heike A. Bischoff-Ferrari’s insights provide valuable guidance on how omega-3 fatty acids, when combined with other healthy practices, could play a crucial role in extending healthspan and delaying the biologically aging process. With more research, the potential health benefits of these interventions could become even more pronounced.
