February 22, 2022 – 07:51
Thecla van Wageningen: Glial cells in white and grey matter: relevance for multiple sclerosis?
Van Wageningen studied the role of various brain cells in multiple sclerosis (MS), in particular the local inflammatory cells. She saw that the inflammatory cells in white and gray matter differ greatly. They differ, among other things, in shape and in the type of proteins on the surface. In addition, there is only a ten percent overlap in genetic information between the inflammatory cells in the white and gray matter. Our brains are made up of white matter and gray matter. The gray matter processes information and contains the cell bodies of nerve cells. The white matter contains the long extensions of the nerve cells and provides communication between the nerve cells. Van Wageningen discovered that the inflammatory cells from the white and gray matter react differently to inflammatory factors. The damage in the gray and white matter of the brain is also very different. There are many inflammatory cells in the white matter, but hardly any in the gray matter. This is especially true in progressive forms of MS. As a result, current MS drugs have less effect on preventing damage to the gray matter. Van Wageningen therefore concludes that inflammatory cells in the white and gray matter react differently, depending on their environmental situation.
MS is characterized by damage in the brain that causes the protective covering around nerves to disappear and the nerve cells themselves become damaged.
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Editorial Medicalfacts/ Janine Budding
I studied physiotherapy and health care business administration. I am also a registered Independent client supporter and informal care broker. I have a lot of experience in various positions in healthcare, the social domain and the medical, pharmaceutical industry, nationally and internationally. And have broad medical knowledge of most specialties in healthcare. And of the health care laws from which health care is regulated and financed. Every year I attend most of the leading medical conferences in Europe and America to keep my knowledge up-to-date and to keep up with the latest developments and innovations. I am currently studying applied psychology.
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