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because after the diet he is getting back pressure easy? The answer is a study carried out on human and mouse cells, published in the journal Nature by the international research group led by the Federal Polytechnic of Zurich with the coordination of Ferdinand von Meyenn. According to research, fat cells remember itobesity even when you lose weight, thus favoring the fear yo-yo victory which leads to gaining weight again afterwards diet.
The research
The team of scholars sequenced the RNAs in which the altered genes are transcribed in adipose cells of 18 normal weight individuals; then he compared them with adipose cells taken from 20 obese people before and after significant weight loss (equivalent to at least 25% of body mass index) obtained by bariatric surgery.
The same analyzes were also performed on adipose cells from normal weight, overweight and obese mice. The results show that human and mouse adipose tissue cells show changes in gene transcription that are maintained even after weight loss. In addition to transcriptional changes, epigenetic changes have also been observed in mice, i.e. chemical changes that change the way the cell’s DNA is read and transcribed into RNA molecules: the -changes that are linked to disorders in some metabolic processes (such as biosynthesis). of fatty acids and the formation of adipose cells) that persist even after weight loss. According to the researchers, the biomolecular changes that occur in adipose tissue favor the yo-yo effect and in the future they could be the targets of new strategies that aim to improve long-term stress management.
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2024-11-18 17:00:00
#Diet #gain #weight #losing #weight #yoyo #effect #obesity #memory #cells #explanation
What are some effective strategies for individuals seeking to maintain weight loss despite the challenges posed by the fat cells’ memory of obesity?
Thank you for your time today. I am the web editor for world-today-news.com, and we recently published an article titled “Study reveals why after losing weight, it can be difficult to maintain a stable weight.” The article discusses the findings of a study published in the journal Nature, which suggests that fat cells retain memory of obesity even after weight loss, contributing to the yo-yo effect. To better understand this topic, we would like to invite you, as experts in the field of health and wellness, to share your insights on this matter.
Guest 1, as a certified nutritionist, what are your thoughts on the study’s findings? Does this research surprise you, and how significant do you think these results are in terms of shaping future weight loss strategies?
Guest 2, as a personal trainer, you must encounter many clients who have experienced the yo-yo effect. How does this study align with your observations? In your experience, what are the main reasons why some individuals struggle to maintain their weight loss?
Guest 1, could you elaborate more on the biomolecular changes that occur in adipose tissue during weight gain and loss? What are the potential implications of these changes for our understanding of weight management?
Guest 2, what do you believe are the key components of sustained weight loss success? How can individuals overcome the challenges posed by these biomolecular changes and maintain their progress over time?
what are your suggestions for individuals who have lost weight but are still experiencing difficulties maintaining their new weight? What lifestyle adjustments could they make to mitigate the effects of these fat cell memories?
