A recent study warned that Corona patients who receive a specific class of glucose-lowering drugs called SGLT2i They may be at increased risk of a fatal condition, when they become infected with the new Corona virus. Diabetes is a known risk factor for disease and death associated with the Corona virus, in patients with diabetes, rare but serious complications can occur, such as the fatal case of diabetic ketoacidosis (DKA).
According to researchers from Brigham Hospital in the United States, the condition known as diabetic ketoacidosis can arise (DKAWhen disease prevents cells from receiving enough glucose to fuel their work.
Diabetes medicine causes rare complications of Corona–
The current study, published in the journal, cautioned The American Association of Clinical Endocrinologists Clinical Case Reports, That Corona patients who receive medication SGLT2i They may be at risk of developing a subset of complications.
The researchers explained that complications occur when the body’s cells fail to absorb enough glucose and compensate by metabolizing fats instead, which leads to the accumulation of acids called ketones.
They said that diabetic ketoacidosis is characterized by low blood sugar levels, adding that it is more difficult to diagnose.
The FDA warned earlier that the risk of complications may increase for individuals who use medications SGLT2i It works by releasing excess glucose in the urine.
In the current study, scientists studied 5 unusual cases of diabetics with diabetic ketoacidosis that were brought to diabetes inpatient services within two months at the height of the epidemic in Boston.
And they found that the five cases represent a significant increase in the incidence of diabetic ketoacidosis compared to the past two years, and according to the researchers, all the last five cases were observed in Corona patients, who were taking diabetes medication SGLT2i – 3 patients were discharged to rehab facilities, one went home, and one, a 52-year-old man with acute respiratory distress syndrome, died.
Researchers believe that Covid-19 It may particularly exacerbate the risk of diabetic ketoacidosis, but this has been hypothesized by other models that the virus may preferentially destroy insulin-producing cells.
Although the results are observational, not clinical, trial, scientists encourage patients and clinicians to stop using SGLT2i In case of illness.
But at the same time he urged the researchers that patients should continue to monitor blood sugar, and if the disease lasts for a long time or if the blood sugar level is very high, they can talk to their doctor about other forms of treatment.
– .
