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Diabetes Drug Metformin Withdrawn, Contains Chemicals That Cause Cancer

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JAKARTA Diabetes medicine Metformin pulled out. This drug is reported to contain chemicals that can cause cancer .

Reporting from the Daily Mail, Saturday (28/8), this was due to the discovery of unacceptable levels of nitrosodimethylamine (NDMA). NDMA is an organic compound that occurs naturally.

World Health Organization (WHO) says it is possibly human carcinogenic, meaning it can cause cancer. Animal studies have shown the compound to cause colorectal, kidney, stomach and kidney cancers at high exposure.

And for humans research only shows large amounts of the chemical can increase cancer risk, not cause it directly.

From this, Dr Alison Cave, chief safety officer of MHRA (Medicines and Healthcare products) from England, said that he had withdrawn this distribution for the sake of patient safety.

Also Read: Symptoms of Type 2 Diabetes, Toes Shape Signs of High Blood Sugar

“This recall of one batch of Metformin oral solution is a precautionary measure to prevent further exposure,” Cave said.

Meanwhile, quoted from the official site BPOM , the news does not apply in Indonesia. The reason, it was explained that BPOM together with the pharmaceutical industry holding marketing permits in Indonesia had conducted a study on all products containing extended release Metformin circulating in Indonesia.

The results of the study show that Metformin products circulating in Indonesia meet the requirements for the acceptable daily intake of NDMA, which is 96 ng/day. Continuous use above this threshold for a long period of time has the potential to cause cancer/carcinogenic.

Metformin has been shown to be safe and effective in the treatment of patients type 2 diabetes adults, especially in patients who are overweight and whose glucose levels cannot be controlled through special diets and physical activity.

In Indonesia, Metformin is one of the essential drugs and can be used as a single therapy or in combination with other diabetes drugs or with diabetes insulin .

Also Read: Type 2 Diabetes, Severe Pain in Certain Body Parts Signs of High Blood Sugar

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