Dana-Farber Cancer Institute, a renowned cancer research and treatment center, is currently facing an investigation and potential retractions over allegations of data manipulation. The investigation involves numerous papers authored by four top scientists and institute leaders, including CEO Laurie Glimcher and COO William Hahn. While the review process began over a year ago, Dana-Farber officials have recently disclosed that they are in talks with journals to retract one paper and correct others.
The investigation gained momentum when scientific sleuth Sholto David started examining papers co-authored by Dana-Farber researchers in December. David claims to have identified issues with figures in 57 papers, many of which are widely cited. He believes that some of the images were deliberately manipulated to deceive readers, alleging scientific misconduct. Some of these concerns were previously flagged online, while others were first described by David himself.
Dana-Farber’s research integrity officer, Barrett Rollins, emphasized that all allegations reviewed thus far have been deemed credible, meaning they are specific and plausible enough to warrant further investigation. However, he clarified that “credible” does not necessarily imply that the allegations are true. Rollins also mentioned that ongoing scientific misconduct investigations involve some of the papers identified by David.
Dana-Farber spokesperson Ellen Berlin stressed that the presence of image discrepancies in a paper does not automatically indicate misconduct. She highlighted the importance of conducting a careful examination of the original data before drawing conclusions about intent. Berlin emphasized the institute’s commitment to accountability and integrity, stating that every inquiry about research integrity is thoroughly examined.
While honest mistakes can occur in research papers, Sidd Jaiswal, a pathologist and cancer researcher at Stanford University, believes that they do not necessarily reflect bad intent on the part of scientists. Jaiswal acknowledges that numerous analyses are involved in producing a final document, making it possible for mistakes to happen. However, he emphasizes the importance of correcting such mistakes promptly.
The investigation into data manipulation allegations at Dana-Farber Cancer Institute is ongoing, with discussions underway to retract one paper and correct others. The institute remains committed to maintaining a culture of accountability and integrity in its research practices. As the investigation progresses, it is crucial to ensure a thorough examination of the allegations and take appropriate corrective actions.
