Creating a pill that brings memory back to Alzheimer’s patients Find out the details

Researchers at the University of California, Los Angeles, USA, revealed… A possible treatment for Alzheimer’s disease No surgery is required and it can be taken orally in the form of pills or syrup, because scientists have discovered that this medicine can … Brain functions Missing because of Alzheimer’s disease, according to the “Market Watch” website.

“There is no drug like this on the market or experimentally proven to do this for Alzheimer’s patients,” said UCLA neuroscience professor and study author Istvan Modi.

It is believed that about 6.5 million Americans suffer from it Alzheimer’s disease The number is expected to rise rapidly as the world’s population ages.

Worldwide, approximately 55 million people were living with the disease in 2020 and the number is expected to reach 78 million by 2030.

The new drug includes a synthetic molecule called DL-920, which can stimulate and reactivate nerve cells damaged by the disease. Slows the progression of the disease But it cannot prevent any damage.

The research included Alzheimer’s disease And brain diseases The other is in mice, whose brains share many key features with the human brain.

Using selective breeding, the researchers bred mice that had the most closely related major genetic mutations Alzheimer’s disease The disease developed quickly.

They gave the new treatment twice a day for two weeks to some mice, a placebo to other mice, and introduced a third group of mice into the experiment that were not selectively bred and were not infected with mice through a standard memory test called the Barnes maze, where they had to remember how to find their way through a maze to the escape hole.

The mice with Alzheimer’s disease who received the placebo did not do well, and the mice with Alzheimer’s disease who received the treatment did almost as well on the test as those who did not have the disease at all.

Treatment includes stimulation Neurons in the brain To produce key electrical signals, called gamma oscillations, which are common in healthy brains but not in those with Alzheimer’s.

“We reversed functional damage, reduced gamma oscillations and reduced memory function and did not examine structural changes in the brain,” the researchers said.