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Covid-19 is still there. XBB.1.5 is still hot.

Thai weekly report figures Between February 19-25, 2023, the number of people infected with “COVID-19” who were sick until hospitalization was 204 people, 9 people died.

It is expected that the daily number of new infections will be as high as 1,458-2,024 people.

Update the strain of the virus “COVID-19” that has spread around the world Gerstung M from Germany point out that The current situation, XBB.1.5 and its relative XBB.1.9.1, are likely to dominate the global outbreak.

While the BQ.1.x and BA.2.x that used to be very contagious are continually diminishing.

In line with the World Health Organization’s previous risk assessment of XBB.1.5, “XBB.1.5” should continue to expand over the next period.

The nature of the cellular immune system After infection in a person who has been vaccinated before?

Koutsakos M and colleagues from Australia have answered a question that many people have been wondering for a long time… if we have been vaccinated. Unintentionally infected with COVID-19, how will our cellular immune system respond?

…It was previously known that “After infection” will increase the immunity in the blood or antibodies But after a few months Antibodies are reduced.

This research suggests that after infection The cellular immune system is rapidly activated by both CD4 and CD8 T-cells. CD4-type cells are activated as early as 1 day after onset of illness. and increased dramatically, reaching a peak within 5 days after onset of illness

CD8, which plays a role in destroying infected cells, is also activated in response, with the number of CD8 produced varying. and has a response time next to CD4.

When this is the case…Assoc. Prof. Dr. Teera emphasized that Paying attention to health is important for living in the current situation, being careful not to underestimate the environment to be better ventilated than in the past.

Assoc.Prof.Dr.Theera Worathanarat
Assoc.Prof.Dr.Theera Worathanarat

“Wearing a mask properly It will greatly reduce the risk. Both from COVID-19 and PM 2.5, prevent yourself from getting infected. or not re-infected would be the best”

Although the reported number of infected people in Thailand is not so much that it is alarming. Nonetheless, don’t get bored of the information about this subject…

Another update found that “If infected, there will be a problem with COVID. Vaccinated people are less likely to have symptoms of Long COVID. There was also about twice the chance that symptoms would subside than those who weren’t vaccinated.”

Data in this regard come from Tran VT et al. from France. Has published the results of a study in the international medical journal BMJ Medicine (28 February 2023) comparing the symptoms in a group of 910 COVID-19 patients, both in the group… “vaccinated” and “not vaccinated”

With knowledge from various researches increasing Point out the benefits of vaccination. In addition to reducing the risk of severe illness reduce the risk of death and reduce the risk of COVID-19 If infected, it’s Long Covid. Vaccination also tends to reduce symptoms. And there is a greater chance that the long-covid symptoms will subside than without vaccination.

…Please be careful in your life. Protect yourself regularly.

Spreading the illusion that people should be infected in order to have stronger immunity than vaccination is wrong and will cause problems in the future. For victims who believe each infection is at risk of becoming ill, severely ill, dying, or having problems with COVID-19 even after having been vaccinated before.

Therefore, health care and defensive behavior is therefore important Especially during the epidemic…“it’s not really calm yet”

Late last month, the World Health Organization issued a risk assessment report for the “Omicron” substrain XBB.1.5, which is a subspecies arising from the crossbreeding of the virus in the BA.2 line. The report has been found in 74 countries around the world

During XBB.1, there is a genetic change that reduces the binding of the virus to the ACE2 receptor on the cell surface. But when there was a mutation to XBB.1.5, it was found that the changed genetic location was 486P.

Enhances the binding capacity of the ACE2 receptor at the target cell surface. As a result, this subspecies has an outbreak that spreads faster than before.

while avoiding that immunity It is clear that XBB.1.5 is immune-resistant as XBB.1, which is considered to be one of the most immune-resistant viruses among all substrains of omikron that have existed.

this immune resistance As a result, the antibodies from older vaccines are insufficient to neutralize the virus. But current data suggests that Immunization with the new version, the bivalent vaccine, has been modified to immunize against Omicron BA.5, producing higher levels of antibodies than the original vaccine.

However, the antibody level after the booster injection will decrease over time. But it is believed that the body’s cellular immune system will continue to work to fight the virus when infected. and can help reduce the risk of serious illness

In terms of severe illness from XBB.1.5, the available data suggest that its severity is similar to that of previous strains and that the altered genotype of XBB.1.5 is not expected to be affected by XBB.1.5 loci. The ability to aggravate the illness

In summary, it is expected that “XBB.1.5” will continue to cause further expansion of the outbreak. due to information about various performance areas mentioned above

defense spell Still have to continue to do so, don’t let the lack of defects… Should conduct daily life consciously, not carelessly, protect yourself regularly. Watch out for risky behavior. risky place Improve ventilation at home, at work, at school, where to eat and drink.

Wearing a mask correctly can greatly reduce the risk. both from COVID-19 And tiny, toxic PM 2.5 dust… Now around us, there are still people who are infected, both adults and children, with mild illnesses, but always be aware of the long-term effects like Long Covid.

“Non-infected” or “Never re-infected”…is the best.

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