Home » Health » Combined corona mutation discovered in Great Britain | Knowledge & Environment | DW

Combined corona mutation discovered in Great Britain | Knowledge & Environment | DW

One evil seldom comes alone: ​​the first cases of the British virus variant have been discovered in Great Britain, which also contain a genetic modification of the South African virus line.

This is worrying because it could combine two negative properties – the British variant B.1.1.7 already makes the virus much more contagious. Unlike the British mutant, the even more contagious South African corona variant 501Y.V2 also carries the mutation E484K – the same mutation that can also be found in two Brazilian variants.

Possible danger also for vaccinated and convalescent people

The mutations are said to be particularly contagious in young people under the age of 20. In addition, the E484K mutation ensures that the neutralizing antibodies that you have in you through a vaccination or a survived corona infection no longer bind to the virus as stably.

It is only through extensive sequencing that it is possible to find out which virus variants are where

This may not only reduce the effectiveness of existing vaccines, but those who have already recovered could possibly become infected again with the virus. Such isolated multiple infections with E484K mutations have already been reported from Brazil.

Sequencing gives a more precise overview

Since the British health authorities sequence the samples taken much more intensively than, for example, the German, there is much more precise information from the United Kingdom about which virus variants are currently on the move.

AfterAngaben der New and Emerging Respiratory Virus Threats Advisory Group (Nervtag) eleven of these mutation combinations were found in 200,000 virus sequences examined. It is highly likely that there will be more such cases.

“Worrying Development”

The American epidemiologist Eric Feigl-Ding of the Federation of American Scientists described this development as “NOT GOOD”. “The virus is such a beast”.

The virologist Julian Tang from the University of Leicester described the cases that have occurred as a “worrying development”. A further spread could one “Melting pot” will enable various new variants, Tang told the BBC. It is now all the more important that people follow the lockdown rules and that the corona cases are contained. Otherwise, the virus could not only spread further, but also develop further.

If these mutation combinations prevail, this would make it much more difficult to contain the pandemic. If more people become infected in less time, this could cause the already overloaded health systems to collapse.

Vaccine effectiveness under scrutiny

We are now working under high pressure to see how the already approved vaccines cope with the mutations and mutation combinations. According to Biontech / Pfizer, their vaccine is also highly effective against the mutant from Great Britain and South Africa. According to one information, the vaccine from competitor Moderna works with the British variant, but it is six times less effective with the South African variant, according to epidemiologist Feigl-Ding in his tweet.

At the same time as testing for effectiveness, vaccine producers around the world are already developing appropriate updates for their vaccines that are adapted to the new virus variants. But it is well known that development, testing, approval, production and vaccination take time.

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