10.04.2023
Through previous studies, it was shown that cold can extend life, but the scientific explanation remained unclear. Now German researchers have come up with amazing results that they hope will help them treat diseases like Alzheimer’s.
Lower body temperature may help extend life, which has been proven by many studies studies conducted on many organisms, including cold-blooded animals such as fish, flies, and mammals.
In nematodes, for example, it was found that lowering their temperature from 20 to 15 degrees Celsius greatly extends their life. The same applies to mice, where a 0.5°C drop in body temperature had a clear effect.
The results of previous studies also showed the effect of low temperature the body on aging in humans. The reason for this was previously unclear. Now a team of researchers from the University of Cologne (Cologne) in Germany has presented a possible explanation for this phenomenon.
They examined nematodes as well as cultured human cells. Both carried the genetic material for two neurodegenerative diseases – diseases of the nervous system caused by a progressive decrease in nerve cells, most notably amyotrophic lateral sclerosis (ALS) and Huntington’s disease.
These diseases develop with age and appear as a result of harmful accumulations of deposits protein with the body.
Eliminate clumping of proteins
In their study, the results of which were published in the journal Nature Aging, it was revealed Researchers Colin reports that proteins that tend to clump together were shed by a cellular mechanism when the temperature dropped slightly—in both nematode worms and human cells. This prevented the build-up of protein deposits associated with amyotrophic lateral sclerosis (ALS) and Huntington’s disease.
The results thus suggest that even a slight decrease in body temperature can extend life.
The researchers hope that promising new approaches to treatment can be developed diseases associated with age.
considered as aging The biggest risk factor for various nervous system diseases, in which protein aggregation occurs. In addition to Huntington’s disease and amyotrophic lateral sclerosis (ALS), these diseases also include Alzheimer’s and Parkinson’s.
A.M./ A.H
