“Clostridium difficile disease” abdominal pain and severe diarrhea “fecal transplant treatment” has a success rate of over 90%! |. at 730

72Mr. Sun, who is 6 years old, suffers from diabetes, hypertension and chronic kidney disease.5I have been suffering from diarrhea and abdominal pain for several months and I have to go to the toilet every day.10More than once, and he wants to run to the toilet as soon as he eats, he has to put a diaper on when he goes out all day and feels depressed He has to get up also in the middle of the night to go to the toilet, which will adversely affect the quality of sleep, weight loss8Kilogram, food greatly reduced.

Clostridium difficile infection causes painful diarrhea, bloody stools and fever Serious risk of death

Li Boxian, director of Linkou Chang Gung Microbacteria Treatment Center, explained that the above patient’s stool test showed Clostridium difficile infection After oral antibiotic treatment, it recurred shortly after each time it came on, causing unspeakable suffering. With the encouragement and arrangement of his children, he was sent to the Linkou Chang Gung Microbacteria Treatment Clinic After a professional evaluation, he chose to be hospitalized to receive colonoscopy microbiota implant treatment. He returned home the next day after the treatment and had a follow-up visit a week later, Mr. Sun, who was in good spirits, said that he no longer had diarrhea after the treatment and could go out. usually for dinner with friends. .

Li Boxian explained that Clostridium difficile disease(Clostridioides difficile infection, CDI)It is an intestinal infection caused by Clostridium difficile. Symptoms include severe diarrhoea, abdominal pain, bloody stools and fever, and severe cases can be fatal. The high recurrence rate after antibiotic treatment has become a problem in modern medical treatment. It wasn’t until microflora implant therapy became popular that the situation improved.

microflora implantation treatment The success rate of fecal transmission in healthy people is as high as94%

Li Boxian described the microflora implant treatment(Fecal Microbiota Transplantation, FMT)It refers to transplanting a healthy donor’s feces into the patient’s intestines after surgery to restore the intestinal micro-ecosystem.2013A New England Journal study proved that once againCDIthe success rate of microflora implant treatment is as high as94%far more than antibiotic treatment31%. therefore,FMTIt has become a treatment method recommended by foreign guidelines, and a related preparation is also approved by the US Food and Drug Administration.

FMTNot only used for rescue treatment or recyclingCDIit can also effectively treat intestinal diseases such as inflammatory bowel disease, irritable bowel syndrome, obesity, and enteritis caused by graft-versus-host disease. Through its gut-brain axis mechanism, it has also begun to be used in the treatment of cranial nerve diseases such as autism, Parkinson’s disease, and depression. Some studies show thatFMTIt can improve the effectiveness of immunotherapy in cancer patients, showing its advanced potential in modern medicine.

Probiotics have difficulty colonizing the intestines Difficulty treating disease alone

So why not just take probiotics? Li Boxian said that this is because oral probiotics usually contain only one to several types of beneficial bacteria, and it is a very difficult process for these single bacteria to go through​​​​ gastric acid successfully colonize and grow in the intestines. They have to fight and replace the original bacteria in the gut, which is very challenging for probiotics that are only used for health care, so it is difficult to use probiotics for diseases that treatment only. But,FMTIt is to transplant a whole healthy micro-ecosystem, like a well-organized army, which can effectively rebuild the patient’s intestinal flora, thus achieving the effect of treating the disease.

【This article has been granted”Health Medical Network“Reprinted with permission. 】

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