pandemic
Drosten explains: This is why the corona virus becomes harmless
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Christian Drosten has expressed confidence in mutations in the coronavirus and treatment with nasal sprays and inhalers.
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Drosten: Germany could escape second Corona wave
– Virologist Christian Drosten believes it is possible that Germany will be spared a second wave of corona. “Maybe we’ll miss a second shutdown,” said the virologist from the Berlin University Hospital Charité to the news magazine “Spiegel”.
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Berlin. Christian Drosten, Director of the Institute of Virology at the Charité Berlin, has in his The Corona Virus Update podcast confident about the effect of nasal sprays and inhalers in the fight against that Corona virus shown. The basis of his statement was the results of one study a group of researchers from the University of North Carolina.
The researchers want to have found that the virus prefers its way into the respiratory tract nose takes. The explanation for this is that there are a particularly large number of ACE2 receptors in the nasal mucous membrane, via which the coronaviruses enter the cells, where they multiply. The viruses would practically be breathed down into the lungs from the nasal mucous membranes, where they sometimes cause serious damage.
“It is worth considering whether to go for inhalation therapy and later vaccination,” said Drosten. The first substances that hinder the multiplication of the corona virus are already known. Remdesivir is one of them. On the basis of the study, one must now consider whether it can also be considered as an early stage of an illness Nasal spray or as an inhaler for the lungs.
“There is a big difference whether an active substance has to penetrate the blood through the intestine and from there into the affected tissue or whether this can be done directly.” However, said substances do not yet exist in the form required, and pharmaceutical companies already do worked on it.
Mask should also cover the nose
In the course of the knowledge of the nose as the preferred target organ for Sars-Cov-2, Drosten also commented on the correct wearing of one Mouthguard. “Well, letting your nose hang out is of course not a good thing,” said Drosten. To know that, however, the results of the study would not have been needed.
“I think that one can assume that if the virus is expelled from the nose it will also be expelled properly.” It is not important whether the virus is mainly in the nose or in the lungs.
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According to the study, coronavirus is particularly viable
Drosten also commented on another podcast from Oxford University. This had examined the development of different populations of the coronavirus.
“The viruses are already differentiating a bit and we have Mutationsthat differentiate the different branches of the young family tree, ”Drosten explained about the evolution of Sars-Cov-2.
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The study examined a total of 405 virus populations and found that in some people there were two different virus populations of SARS-CoV-2 were present at the same time. You could imagine that as a green and red variant, said Drosten. Almost all patients had only one of the two. “But there are some patients who mixed it up. The so-called colorful patients. “
At first, that’s pretty bad news. If two different virus strains would spread independently of one another and then meet again, this would be a good example Survivability of the virus. Second, it would show that Sars-Cov-2 viruses, despite different developments, can multiply together when they meet again. That in turn would favor mutations.
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Coronavirus soon a simple cold?
“Populations of mixed compositions ensure that the virus has a better chance of adapting to humans,” explained Drosten. However, this is not necessarily bad news. “This adjustment can make it easier to carry over, but it stays in the nose and becomes easy sniff becomes.”
A mutation of the coronavirus towards a more severe one Course of the disease could also happen, but it makes no sense for the development of the virus due to evolution. If symptoms appear faster and more violently, people would isolate themselves earlier and thus infect fewer people, Drosten said. “This is why virus epidemics generally weaken.” There are many examples from the past.
“The virus will in any case become more harmless – alone due to population immunity,” Drosten continued. But maybe play that too evolution of the corona virus still matter.
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