Do you often feel irregular heartbeat, loss of appetite, and muscle weakness? Be careful! It may be caused by hypercalcemia caused by sarcoma! “Sarcoma” is an inflammatory granulomatous disease that most commonly occurs in the lungs, skin, lymph nodes, etc.; about 10% to 17% of patients are accompanied by hypercalcemia (calcium ion concentration in the blood). too high) phenomenon.
A 45-year-old Mr. Feng is a patient with end-stage renal disease. He has been receiving hemodialysis treatment for more than 20 years. His condition has always been well controlled, but recently he often has symptoms of inexplicable fatigue, loss of appetite, and body bone aches. After medical examination, it was found to be caused by “sarcoma” It was caused by a spike in blood calcium. Fortunately, he was fine after seeking medical treatment.
Excessive calcium ion concentration may lead to coma and death
Wang Botang, the attending physician at the Internal Medicine Intensive Care Unit of National Cheng Kung University Hospital, said that although most patients with mild hypercalcemia will not experience any symptoms, if they are not paid attention to and are careful, the concentration of calcium ions in the blood will rise rapidly, which may cause severe complications. Consciousness, arrhythmia, and even death may occur!
However, why does excessive calcium ion concentration in the blood have such serious effects on the human body? Dr. Wang Baitang said that calcium ions play a very important role in the human body. Everything such as nerve conduction, muscle contraction, blood coagulation and cell enzyme function are all affected by calcium ions. Hypercalcemia affects almost the whole body. Nervous system abnormalities are prone to symptoms such as coma, depression, and muscle weakness; kidney disease symptoms such as polyuria, stones, renal failure, etc.; cardiovascular disease symptoms such as arrhythmia, vascular calcification, etc.; and nausea and vomiting. , loss of appetite, constipation and other gastrointestinal discomforts. These symptoms are related to blood calcium concentration and the rate of increase in calcium ions.
Hypercalcemia affects almost the whole body, and abnormalities in the nervous system can easily lead to symptoms such as coma, depression, and muscle weakness.
Hypercalcemia is divided into three levels: mild, moderate and severe.
The normal concentration of calcium in the body also has a certain range, generally between 8.4 and 10.5mg/dl. If it exceeds it, it means there is a problem of hypercalcemia. Depending on its severity, hypercalcemia can be divided into:
Mild hypercalcemia:Blood calcium concentration 10.5~11.9mg/dl
Moderate hypercalcemia:Blood calcium concentration 12~13.9mg/dl
Severe hypercalcemia:Blood calcium concentration is 14~16mg/dl; also known as hypercalcemic crisis.
In addition to general granulomatous diseases (tuberculosis, sarcoma), primary hyperparathyroidism and malignant tumors; long-term bed rest, drug overdose (vitamin A, lithium salts) and familial hypouria and hypercalcemia inheritance, etc. , will lead to the occurrence of hypercalcemia. In addition, kidney disease patients who need to undergo hemodialysis should consider whether the calcium ion concentration of the dialysate they use is too high; or there is the possibility of supplementing calcium tablets and vitamin D, aluminum poisoning, and renal hyperparathyroidism. Deterioration and other factors.
Find the root cause of hypercalcemia and treat the symptoms
Dr. Wang Baitang reminded that hypercalcemia is a problem that is often ignored in clinical practice. If you only prescribe calcium-lowering drugs without identifying the root cause of hypercalcemia, it may be life-threatening. Therefore, once the problem of hypercalcemia is discovered, relevant medical history should be confirmed and appropriate examinations should be carried out to find out the real culprit and prescribe the right medicine. This is the fundamental way to stay away from the crisis of hypercalcemia.
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Source: Chinese Health Network
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2023-09-29 01:00:00
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