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A person is said to have high blood sugar if the fasting blood sugar level is more than 125 mg/dL, or greater than 180 mg/dL two hours after eating.
Certain conditions can raise blood sugar levels by interfering with insulin’s ability to transport glucose out of the bloodstream. When this happens, you have high blood sugar, which puts you at risk for prediabetes, diabetes , and associated complications.
Here are the causes of high blood sugar in non-diabetics reported from Very Well Health, Sunday (12/9/2021).
Also Read: Symptoms of Type 2 Diabetes, Swollen Legs a Sign of High Blood Sugar
Sindrom Cushing
People with Cushing’s syndrome are at increased risk of developing impaired blood sugar tolerance and high blood sugar as a result of elevated cortisol levels throughout the body. Cortisol is a hormone that counteracts the effects of insulin by blocking the uptake of blood sugar from the bloodstream, thereby increasing insulin resistance and maintaining high blood sugar levels. Elevated cortisol levels also partially decrease insulin release from its production site in the pancreas.
Corticosteroid drugs are often prescribed to reduce inflammation throughout the body, but can lead to the development of Cushing’s syndrome and high blood sugar because they activate specific enzymes that increase the conversion of non-carbohydrate molecules to glucose (gluconeogenesis). Corticosteroids also impair pancreatic cell function by inhibiting cell signaling pathways involved in insulin release from the pancreas.
Pancreatic Disease
Diseases of the pancreas such as pancreatitis, pancreatic cancer and cystic fibrosis can cause high blood sugar because the cells of the pancreas are damaged in these conditions. Insulin is produced and released from the cells of the pancreas. With inflammation and damage to the pancreas, the cells of the pancreas are no longer able to produce enough insulin to remove glucose from the blood to control blood sugar.
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