03/17/2020 1:49 PM
(Act. 17.03.2020 13:49)
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Individual medical opinions and subsequent fake news have recently linked Covid-19 disorders to certain blood pressure medications. After the rector of MedUni Vienna, Markus Müller, and the Viennese pharmacologist Michael Freissmuth at the weekend, the Austrian Cardiological Society also reacted on Tuesday. Her conclusion: nothing to it.
In any case, the reports have caused uncertainty in many patients with high blood pressure and heart failure, since ACE inhibitors and angiotensin receptor blockers are used very frequently and effectively in these diseases, the specialist society found.
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“Immunosuppressed patients, older multimorbid patients, patients with previous lung disease, but also diabetics and patients with chronic heart diseases are generally classified as high-risk patients and should therefore take special care. As the Austrian Cardiological Society (ÖKG) we recommend existing medication with ACE- It is imperative to keep inhibitors and angiotensin receptor blockers. Stopping medication or switching to other preparations is not indicated and should be avoided because of the risk of an acute heart attack or stroke, “emphasized Peter Siostrzonek (Ordensklinikum Linz), President of the ÖKG.
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The postulated connection between a COVID-19 infection and the drugs mentioned is purely speculative and is derived from animal experiments, according to which SARS-CoV-2 is bound to the so-called ACE2 receptor in the lungs and, on the other hand, ACE2 under therapy with ACE- Inhibitors and angiotensin receptor blockers are increasingly formed. Instead, other studies – also speculatively – provide opposite indications that the corresponding therapy could even weaken the course of a COVID-19 infection. Siostrzonek concludes, however, that there is no conclusive scientific evidence for a connection in one direction or the other.
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There is no scientific evidence for a negative effect of taking nonsteroidal anti-inflammatory drugs or ACE inhibitors or sartans in Covid 19 patients or infected people, said Saturday evening the MedUni Vienna Rector Markus Müller and the head of the MedUni Vienna Center for Physiology and pharmacology, Christian Freissmuth, told APA. The European Society for Cardiology (ESC) had already commented on the question.
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“These speculations about the safety of ACE inhibitors or angiotensin receptor blockers have no solid scientific basis. In reality, there is evidence from animal studies that these drugs may have a protective effect against severe lung complications. So far, there are none Data (about the effect; note) in humans “, it had said in an ESC statement.
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